QUERCETIN

PRODUCT IDENTIFICATION
CAS NO. 117-39-5
6151-25-3 (Dihydrate)

QUERCETIN

EINECS NO.

204-187-1

FORMULA C15H10O7
MOL WT. 302.24

H.S. CODE

 2932.99.6100

TOXICITY

  
SYNONYMS Xanthaurine; Meletin; Quercetol; Quertine; Sophoretin;
2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one Dihydrate; Cyanidelonon 1522; 3,3',4',5,7-Pentahydroxyflavone; 3',4',5,7-tetrahydroxyflavon-3-ol Dihydrate; C.I. Natural Red 1; 3,5,7,3',4'-pentahydroxyflavone; C.I. 75670; C.I. Natural yellow 10; C.I. Natural Yellow 10 & 13;

SMILES

c12c(oc(c3cc(c(O)cc3)O)c(c1=O)O)cc(O)cc2O

CLASSIFICATION

Flavonoid, Flavonol, Antioxidant

EXTRA NOTES

A flavonol widely distributed in plants. It is an antioxidant, like many other phenolic heterocyclic compounds. Glycosylated forms include RUTIN and quercetrin.
Overall Carcinogenic Evaluation: Group 3
Other RN: 73123-10-1, 74893-81-5

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE yellow crystalline powder
MELTING POINT 310 - 317 C
BOILING POINT Sublimes
SPECIFIC GRAVITY  
SOLUBILITY IN WATER Practically insoluble
pH  
VAPOR DENSITY

8.1

AUTOIGNITION

 

NFPA RATINGS Health: 2 Flammability: 0 Reactivity: 0

REFRACTIVE INDEX

  
FLASH POINT 112 C
STABILITY

Stable under ordinary conditions. Moisture sensitive.

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking - Quercetin

Google Scholar Search - Quercetin

Drug Information Portal (U.S. National Library of Medicine) - Quercetin

PubChem Compound Summary - Quercetin

Drug Bank -  Quercetin

KEGG (Kyoto Encyclopedia of Genes and Genomes) - Quercetin

Chemical Entities of Biological Interest (ChEBI) - Quercetin

http://www.ncbi.nlm.nih.gov/ - Quercetin

Human Metabolome Database - Quercetin

Material Safety Data Sheet - Quercetin

http://toxnet.nlm.nih.gov/
Hazardous Substances Data Bank - Quercetin

Local:
Quercetin, a common bioflavonol composed of two benzene rings linked with a heterocyclicpyrone ring (aromatic trimeric heterocyclic), is a water-soluble pigment synthesized or naturally occurring in the rind and bark of numerous plants. It, chemically 2-(3,4-dihydroxyphenyl)-3,5,7- trihydroxy- 4H-1-benzopyran-4-one, is a yellow to greenish crystalline powder melting at 302 C. Bioflavonoids are called phytochemicals, Vitamin P, and Vitamin C2. There are about 2000 known bioflavonoids including catechin, citrin, eriodictin, hesperetin, hesperidin, nobiletin, quercetin, rutin, sinensetin, and tangeretin. Vitamin P is not a dietary essential but is known to have the effect on capillary disorders. It increases the strength of the walls of the blood capillaries and regulates their permeability. It may have an contribution to the total antioxidant activity and detoxifiers. It may enhance the action of Vitamin C. It is considered that it lowers down cholesterol levels if it taken with Vitamin C. It is also know to have pharmacological action as an anti-inflammatory ,antihistaminic and antiviral agent.

SALES SPECIFICATION

APPEARANCE

 yellow crystalline powder

ASSAY

96.0% - 102.0%

LOSS ON DRYING

9.0 - 11.0%

SULFATE

0.001% max

CHLORIDE

0.001% max

SULFATED ASH

0.2% max

HEAVY METALS

20ppm max

TRANSPORTATION
PACKING
 
HAZARD CLASS 6.1 (Packing Group: III)
UN NO. 2811
OTHER INFORMATION
Hazard Symbols: T, Risk Phrases: 23/25-40, Safety Phrases: S: 22-36/37/39-45

GENERAL DESCRIPTION OF FLAVONOID
Flavonoid is any member of a class of widely distributed biological natural products containing aromatic heterocyclic skeleton of flavan (2-Phenylbenzopyran) but no nitrogen in plants. Generally, flavonoids are biological pigments providing colours from red to blue in flowers, fruit and leaves. Besides their coloring in plants, flavonoids have important roles in the growth and development of plants; protection against UV-B radiation; forming antifungal barriers; antimicrobial, insecticidal and oestrogenic activities; plant reproduction. Flavonoids also exhibit a wide range of biological properties including anti-microbial, insecticidal and oestrogenic activities. Flavonoids are usually classified into main 6 subgroups as below plus flavans, neoflavonoids, flavonols, aurons, catechins according to the structural patterns.
  • Flavonols (Hydroxy derivatives of flavone): Fisetin, Galangin, Kaempferide, Kaempferol, Morin, Myricetin, Myricitrin, Quercetin, Quercetrin, Rhamnetin, Robinin, Rutin, Spirenoside
  • Flavones (skeleton: 2-phenylchromen-4-one): Apigenin, Baicalein, Chrysin, Diosmetin, Diosmin, Flavone, Luteolin, Rpoifolin,Tangeretin, Techtochrysin, Rhamnazin, Nobiletin, Natsudaidain.
  • Isoflavones (skeleton: 3-phenylchromen-4-one): Daidzin, Genistein, Irilone, Luteone, Prunetin, Pratensein,
  • Flavonones (derivation by reduction of the 2(3) C=C bond): Eriodictyol, Hesperidin, Hesperetin, Likvirtin, Naringin; Naringenin; Pinocembrin
  • Flavanols (derivation by reduction of the keto group):(+)-Catechin, (+)-Gallocatechin, (-)-Epicatechin (EC), (-)-Epigallocatechin (EGC), (-)-Epicatechin 3-gallate (ECG), (-)-Epigallocatechin 3-gallate (EGCG), Theaflavin, Theaflavin 3-gallate, Theaflavin 3'-gallate, Theaflavin 3,3' digallate, Thearubigins
  • Anthocyanidins (aglycones of the glycoside anthocyanins): Cyanidin, Delphinidin, Diosmetinidin, Guibourtinidin, Fisetinidin, Luteolinidin, Malvidin, Pelargonidin, Peonidin, Robinetinidin, Tricetinidin, Capensinidin, Petunidin, Europinidin, Aurentinidin, Columnidin, 5-Desoxy-malvidin, 5-Desoxy-peonidin, Hirsutinidin, Rosinidin




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