ALPHA-CYCLODEXTRIN (CYCLOHEXAAMYLOSE)

alpha-CYCLODEXTRIN HYDRATE
PRODUCT IDENTIFICATION
CAS NO.	10016-20-3
EINECS NO.	233-007-4
FORMULA	C₃₆H₆₀O₃₀
MOL WT.	972.85
H.S. CODE	2940.00.6000
TOXICITY
SYNONYMS	Cyclohexaamylose; Alpha-Schardinger dextrin;
Alfadex; alpha-Cycloamylose; alpha-Dextrin; Cyclohexaamylose carbonate; Cyclomaltohexaose; Cyclomaltohexose; 5,10,15,20,25,30-Hexakis (hydroxymethyl)- 2,4,7,9,12,14,17,19,22,24,27,29- dodecaoxaheptacyclo (26.2.2.23,6.28,11.213,16.218,21.223,26) dotetracontane- 31,32,33,34,35,36,37,38,39,40,41,42-dodecol; Other RN: 23513-50-0, 41871-62-9, 47910-04-3
SMILES	O1[C@@H]2[C@@H](O[C@H](O[C@@H]3[C@@H](O[C@H](O[C@@H] 4[C@@H](O[C@H](O[C@H]5[C@H]([C@H]([C@@H](O[C@H]6[C@H] ([C@H]([C@@H](O[C@H]7[C@H]([C@H]([C@@H]1O[C@@H]7CO)O)O) O[C@@H]6CO)O)O)O[C@@H]5CO)O)O)[C@@H]([C@@H]4O)O)CO)[C@ @H]([C@@H]3O)O)CO)[C@@H]([C@@H]2O)O)CO
CLASSIFICATION	Cyclodextrins are low molecular weight organic molecules which form watersoluble complexes with various compounds (guests); Enzyme model
PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE	white powder
MELTING POINT	278 C
BOILING POINT
SPECIFIC GRAVITY
SOLUBILITY IN WATER	Soluble
pH
VAPOR DENSITY	33.5
AUTOIGNITION
NFPA RATINGS	Health: 1 Flammability: 1 Reactivity: 0
REFRACTIVE INDEX
FLASH POINT
STABILITY	Stable under normal conditions.
EXTERNAL LINKS & GENERAL DESCRIPTION
Wikipedia Linking Cyclodextrin Database Google Scholar Search http://www.eurocdsoc.com/ Cyclodextrins are a group of structurally related natural products formed during bacterial digestion of cellulose. These cyclic oligosaccharides consist of (α-1,4)-linked α-D-glucopyranose units and contain a somewhat lipophilic central cavity and a hydrophilic outer surface. Due to the chair conformation of the glucopyranose units, the cyclodextrins are shaped like a truncated cone rather than perfect cylinders. The hydroxyl functions are orientated to the cone exterior with the primary hydroxyl groups of the sugar residues at the narrow edge of the cone and the secondary hydroxyl groups at the wider edge. The central cavity is lined by the skeletal carbons and ethereal oxygens of the glucose residues, which gives it a lipophilic character. The polarity of the cavity has been estimated to be similar to that of an aqueous ethanolic solution. Local: Cyclic structure oligomers of glucose ( called cyclodextrins) are obtained from the starch digests of the bacteria Bacillus macerans. The individual glucose units are connected by 1,4 bonds. The most abundant cyclodextrins are alpha, beta and gamma cyclodextrin which have 6,7 and 8 glucose units respectively. The interior cavity is hydrophobic and the outside of the molecule is hydrophilic. The enhanced of characteristics such as stability, aqueous solubility, and reduced volatility, can be modified through mainly propoxylation reactions of them. Potential applications of cyclodextrins include water-soluble pharmaceuticals, prolonged drug release, tabletting and herbicides and pesticides. Some examples of commercially available cyclodextrin, or derivatives thereof, are as follows: alpha-Cyclodextrin (CAS #: 10016-20-3) alpha-Cyclodextrin phosphate Sodium salt (CAS #: 199684-60-1) alpha-Cyclodextrin, sulfated Sodium salt Hydrate (CAS #: 699020-02-5) Hexakis (2,3,6-tri-O-acetyl)-alpha-cyclodextrin Hexakis (2,3,6-tri-O-methyl)-alpha-cyclodextrin Hexakis(2,3,6-tri-O-octyl)-alpha-cyclodextrin (CAS #: 140395-31-9) Hexakis-6-bromo-6-deoxy-alpha-cyclodextrin (CAS #: 53784-82-0) Hexakis-6-iodo-6-deoxy-alpha-cyclodextrin (CAS #: 131105-41-4) Hexakis (6-O-tertbutyl-dimethylsilyl)-alpha-cyclodextrin Butyl-alpha-cyclodextrin Succinyl-alpha-cyclodextrin (2-Hydroxypropyl)-alpha-cyclodextrin (CAS #: 128446-33-3) beta-Cyclodextrin (CAS #: 7585-39-9) beta-Cyclodextrin Hydrate (CAS #: 68168-23-0) beta-Cyclodextrin phosphate Sodium salt (CAS #: 199684-61-2) beta-Cyclodextrin sulfate beta-Cyclodextrin, sulfated Sodium salt (CAS #: 37191-69-8) Hydroxypropyl-beta-cyclodextrin (CAS #: 94035-02-6) 6-Monodeoxy-6-monoamino-beta-cyclodextrin 6-O-alpha-D-Glucosyl-beta-cyclodextrin (CAS #: 92517-02-7) 6-O-alpha-Maltosyl-beta-cyclodextrin Hydrate (CAS #: 104723-60-6) Heptakis-6-azido-6-deoxy-beta-cyclodextrin Heptakis(2,3-di-O-acetyl-6-O-sulfo)-beta-cyclodextrin Heptasodium salt (CAS #: 196398-66-0) Heptakis-(2,3-di-O-methyl-6-O-sulfo)-beta-cyclodextrin Heptasodium salt (CAS #: 201346-23-8) Heptakis(2,6-di-O-methyl)-beta-cyclodextrin (CAS #: 51166-71-3) Heptakis-(2,6-di-O-ethyl)-beta-cyclodextrin (CAS #: 111689-03-3) Heptakis(2,3,6-tri-O-methyl)-beta-cyclodextrin (CAS #: 55216-11-0) Heptakis(2,3,6-tri-O-acetyl)-beta-cyclodextrin Heptakis-(2,3,6-tri-O-benzoyl)-beta-cyclodextrin (CAS #: 23666-43-5) Heptakis-(2,3,6-tri-O-ethyl)-beta-cyclodextrin (CAS #: 111689-01-1) Heptakis-6-iodo-6-deoxy-beta-cyclodextrin (CAS #: 30754-23-5) Heptakis-6-(dimethyl-tert-butylsilyl)-6-deoxy-beta-cyclodextrin Heptakis-6-bromo-6-deoxy-beta-cyclodextrin Monoacetyl-beta-cyclodextrin Diacetyl-beta-cyclodextrin Triacetyl-beta-cyclodextrin (CAS #: 23739-88-0) Heptakis(3-O-acetyl-2,6-di-O-methyl)-beta-cyclodextrin (CAS #: 131889-29-7) Heptakis-(6-O-maltosyl)-beta-cyclodextrin Heptakis(6-O-sulfo)-beta-cyclodextrin Heptasodium salt (CAS #: 197587-31-8) Heptakis(6-O-t-butyldimethylsilyl-2,3-di-O-acetyl)-beta-cyclodextrin Succinyl-(2-hydroxypropyl)-beta-cyclodextrin (2,6-Di-O-)ethyl-beta-cyclodextrin (2-Carboxyethyl)-beta-cyclodextrin (2-Hydroxyethyl)-beta-cyclodextrin (CAS #: 128446-32-2) (2-Hydroxypropyl)-beta-cyclodextrin (CAS #: 128446-35-5) Butyl-beta-cyclodextrin Methyl-beta-cyclodextrin (CAS #: 128446-36-6) Silyl((6-O-tert-butyldimethyl)-2,3,-di-O-acetyl)-beta-cyclodextrin Succinyl-beta-cyclodextrin gamma-Cyclodextrin (CAS #: 17465-86-0) gamma-Cyclodextrin Hydrate (CAS #: 91464-90-3) gamma-Cyclodextrin phosphate Sodium salt (CAS #: 199684-62-3) Sulfopropyl-beta-cyclodextrin Carboxymethyl-gamma-cyclodextrin Octakis (2,3,6-tri-O-acetyl)-gamma-cyclodextrin Octakis (2,3,6-tri-O-methyl)-gamma-cyclodextrin Octakis (2,6-di-O-pentyl)-gamma-cyclodextrin Octakis-6-(dimethyl-tert-butylsilyl)-6-deoxy-gamma-cyclodextrin Octakis-6-bromo-6-deoxy-gamma-cyclodextrin (CAS #: 53784-84-2) Octakis-6-iodo-6-deoxy-gamma-cyclodextrin (CAS #: 168296-33-1) Octakis (6-O-t-butyldimethylsilyl)-gamma-cyclodextrin Succinyl-gamma-cyclodextrin (2-Hydroxypropyl)-gamma-cyclodextrin (CAS #: 128446-34-4) Acetyl-gamma-cyclodextrin Butyl-gamma-cyclodextrin
SALES SPECIFICATION
APPEARANCE	white powder
PURITY	98.0% min
SPECIFIC ROTATION	+133° ~ +139° (c=10 in H2O on dry basis)
MOISTURE	5.0% max
TRANSPORTATION
PACKING
HAZARD CLASS	Not regulated
UN NO.
SAFETY INFORMATION
`Hazard Symbols: , Risk Phrases: , Safety Phrases: 24/25-28A-37-45`
GENERAL DESCRIPTION OF DEXTRIN
Dextrin is a polymeric carbohydrate which are formed during the hydrolysis of starch to sugars by heat, by acids, and by enzymes. (Maltose, sucrose and lactose are disaccharides of same empirical formula (C₁₂H₂₂O₁₁) but are isomers differs from in structure). Dextrin and starch have the general formula, -[C_x(H2O)_y)]_n- (y = x - 1), in which glucose units are joined to one another usually head-to-tail, but dextrin has a smaller and less complex molecule than starch. Dextrin is soluble in water but is precipitated by alcohol. It's chemical properties rely on the extent of the starch from which they are derived. Some dextrin react with iodine to give a blue color and is soluble in 25% alcohol (called amylodextrin); others a reddish-brown color and soluble in 55% alcohol (called erythrodextrin); and still others yield no color at all with iodine and soluble in 70% alcohol (called achrodextrin). It is also identified by dextrose equivalence (DE) which is a measure of reducing power compared to the standard of 100 (dextrose). The higher DE is the more extent of starch depolymerization. Maltodextrin is the product of low DE. Dextrin forms a strongly adherent paste when mixed with water and it is used as adhesive in the manufacture of gummed tapes, textiles and paper. It is used in producing nutritional products.
PRICE INFORMATION