1-AMINO-4-METHYLPIPERAZINE

PRODUCT IDENTIFICATION

CAS NO. 6928-85-4

1-AMINO-4-METHYLPIPERAZINE

EINECS NO. 230-053-7
FORMULA C5H13N3
MOL WT. 115.18

H.S. CODE

 

TOXICITY

 
SYNONYMS 4-Methylpiperazin-1-amine; 4-methyl-1-Piperazinamine;
SMILES

 

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE clear to light yellow liquid
MELTING POINT  
BOILING POINT

172 - 175 C

SPECIFIC GRAVITY 0.956
SOLUBILITY IN WATER miscible
pH  
VAPOR DENSITY

 

REFRACTIVE INDEX

 

NFPA RATINGS

Health: 1; Flammability: 2; Reactivity: 1

AUTOIGNITION

 

FLASH POINT

 

STABILITY Stable under normal conditions, light and air sensitive

GENERAL DESCRIPTION & APPLICATIONS

Piperazine is a heterocyclic compound containing four carbon atoms and two of nitrogen at 1,4 position ( als called 1,4-hexahydropyrazine). It is a deliquescent crystalline compound melting at 105 C; soluble in water, alcohol, glycerol, and glycols. It is used as a main ingredient of anthelmintics used to treat intestinal roundworms (ascariasis) infection in human and  poultry and to treat pinworms (enterobiasis; oxyuriasis) by altering cell membrane permeability and causing hyperpolarization of the membrane. Piperazine is a moiety in psychoactive drugs. Certain piperazine derivatives are suspected of ecstasy substitutes. Benzylpiperazine is bannaed in many countries. Benzylpiperazine  has been used as a anthelmintic (antiparastic effect). Nitrogen in piperazine ring plays an important role in biological research and drug manufacturing industry including the preparation of anthelmintic, antiallergenic, antibacterial, antihistamic, antiemetic and antimigraine agents. The piperazine ring and piperazine derivatives are important cyclic components in industrial field as raw materials for hardener of epoxy resins, corrosion inhibitors, insecticides, accelerators for rubber, urethane catalysts and antioxidants.

An example of 1-Amino-4-methylpiperazine application is to be used as an intermediate for pharmaceuticals ( Anti-tuberculostatic agent: Rifampicin).

SALES SPECIFICATION

APPEARANCE

clear to light yellow liquid

ASSAY

99.0% min

MOISTURE

0.5% max
TRANSPORTATION
PACKING
180kgs in drum
HAZARD CLASS  
UN NO.  
OTHER INFORMATION
Hazard Symbols: XI, Risk Phrases: 36/37/38, Safety Phrases: 24/25