1-FLUORO-2,4-DINITROBENZENE

PRODUCT IDENTIFICATION
CAS NO. 70-34-8

1-FLUORO-2,4-DINITROBENZENE

EINECS NO. 200-734-3
FORMULA (NO2)2C6H3F
MOL WT. 186.10

H.S. CODE

 2904.90

TOXICITY
SYNONYMS 2,4-Dinitro-1-fluorobenzene
1,3-Dinitro-4-fluorobenzene 2,4-DNFB DNF DNFB   Sanger's reagent 1,2,4-Fluorodinitrobenzene Dinitrofluorobenzene 2,4-Dinitrofluorobenzene
SMILES  

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE clear to yellow crystal
MELTING POINT 28 - 30 C
BOILING POINT

178 C

SPECIFIC GRAVITY

1.475 - 1.485

SOLUBILITY IN WATER Insoluble  (soluble in benzene, propylene glycol, and ether)
pH  
VAPOR DENSITY

 

AUTOIGNITION

 

NFPA RATINGS

  

REFACTIVE INDEX

 

FLASH POINT

 

STABILITY Stable under ordinary conditions

APPLICATIONS
The prefix nitro- indicates the presence of NO2- radical, while nitrate refers to any salt or ester of nitric acid or the NO3- anion. Nitroso- is the prefix indicating presence of the group -NO and azo- is for -N=N- group. Some range of  organic compounds containing nitrogen include nitro compounds (RNO2 ), nitroso compounds (RNO), amines (R3N ), amino acids, and natural alkaloids or nucleotides. The nitrogen ion in nitro compounds is trigonally planar with 120° angles. There are two resonance bonds so that the two oxygens are equivalent. Nitro compounds are strongly basic due to electron withdrawing both inductively and mesomerically. Historically, they are abundant in dyes and explosives. Nitro compounds, organic hydrocarbons having one or more NO2 groups bonded via nitrogen to the carbon framework, are versatile intermediate in organic synthesis.
  • Michael addition
  • Reduction
  • Henry Reaction (Nitro-aldol reaction)
  • Nef reaction
  • O-Alkylation
  • Cycloaddition
  • Substitution, Elimination, Conversion reaction
  • Alkylation, Acylation, and Halogenation

2,4-Dinitrofluorobenzene is used as an intermediate for the synthesis of pesticides and pharmaceuticals such as flurbiprofen (nonsteroidal anti-inflammatory agent). It is used as a reagent ( Sanger's reagent)  to identify the    terminal  amino acids in a protein chain  and to  detection of phenols.

SALES SPECIFICATION

APPEARANCE

 clear to yellow crystal

ASSAY

99.0% min
MELTING POINT 28 - 30 C
TRANSPORTATION
PACKING

40kgs in Drum

HAZARD CLASS 6.1 (Packing Group: II)
UN NO. 2810
OTHER INFORMATION
Hazard Symbols: T, Risk Phrases: 23/24/25/33/42/43/44, Safety Phrases: 28A/37/45

GENERAL DESCRIPTION OF NITROBENZENE

Nitrobenzene (also called nitrobenzol ) is a colourless to pale yellow, oily, highly toxic liquid with the odour of bitter almonds. Nitrobenzene is manufactured commercially by nitration of benzene (also a common air pollutant) using a mixture of nitric and sulfuric acids. Commercially nitrobenzene can be either produced in a batch or by a continuous process. Both batch and continuous processes employing mixed nitric and sulfuric acids are used to make nitrobenzene. The continuous process is favored over the batch process because its production capacity is much larger, it has lower capital costs and it entails more efficient labor usage. Reactors for the continuous process also usually utilized lower nitric acid concentrations, are smaller with more rapid and efficient mixing, and therefore have higher reaction rates. Nitrobenzene undergoes nitration, halogenation, and sulfonation much more slowly than does benzene. It may be reduced to a variety of compounds, depending on the reaction conditions. Most nitrobenzene produced is reduced to aniline smaller amounts are converted to azobenzene, hydrazobenzene (the intermediate for benzidine), and phenylhydroxylamine. Reduction of both the nitro group and the benzene ring affords cyclohexylamine. Nitrobenzene is used as a mild oxidizing agent in the syntheses of quinoline and fuchsin. Nitrobenzene is used to produce lubricating oils such as those used in motors and machinery. Nitrobenzene and its derivatives are used in the manufacture of dyes, drugs, pesticides, polisher, paint, and synthetic rubber.