| CAS
NO. |
288-94-8 |
|
| EINECS
NO. |
206-023-4 |
| FORMULA |
CH2N4 |
| MOL
WT. |
70.04 |
|
H.S.
CODE
|
2933.99 |
|
TOXICITY
|
|
| SYNONYMS |
Tetrazole;
Tetraazacyclopentadiene; 2H-Tetrazole; |
| 1H-1,2,3,4-tetrazole;
1H-四氮唑; TA: |
| SMILES |
|
|
CLASSIFICATION
|
|
|
PHYSICAL
AND CHEMICAL PROPERTIES
|
| PHYSICAL
STATE |
white
to off-white crystalline powder |
| MELTING
POINT |
155
-158 C |
| BOILING
POINT |
Decomposes |
| SPECIFIC
GRAVITY |
|
| SOLUBILITY
IN WATER |
soluble
(23g/100ml at 20 C) |
| pH |
|
| VAPOR
DENSITY |
|
|
AUTOIGNITION
|
|
|
NFPA
RATINGS
|
Health:
1; Flammability: 1; Reactivity: 1 |
|
REFRACTIVE
INDEX
|
|
| FLASH
POINT |
220
C
|
| STABILITY |
Stable
under ordinary conditions |
|
GENERAL
DESCRIPTION & APPLICATIONS
|
| Tetrazole
is one
of a
class of organic heterocyclic compounds
containing a five-membered diunsaturated ring structure
composed of four nitrogen atoms and one carbon atom.
The simplest member of the tetrazole
family is tetrazole
itself,
white
to pale yellow crystalline solids with a weak characteristic
odor; soluble in water and alcohol, melts at 156 C.
Tetrazole is explosive. It is used as a gas generating agent for air
bags. Shipment of tetrazole is available only as a solution in some countries.
Tetrazole
and its derivatives are used for biological activities such
as antiviral, antibacterial, antifungal and antituberculous.
They are used as catalysts in the synthesis of phosphonates.
Oligonucleotide is a short DNA (deoxyribonucleic acid) or RNA (ribonucleic
acid) sequence, typically made up of a few (2–20) covalently linked nucleotides.
In molecular genetics, a short sequence synthesized to match a region where a
mutation is known to occur, and then used as a probe for detecting complementary
DNA or RNA. Oligonucleotides are currently used for genomic,proteomic and drug
discovery technologies. Tetrazole is the traditional oligonucleotide synthesis
activato for good coupling efficiency and to decrease the coupling times. But
there are disadvantages of tetrazole; crystallisation problem from solution
and potential explosive property at room temperature. Some alternatives have
been recommended;
- 5-Ethylthio-1H-tetrazole [CAS RN:
89797-68-2]
5-Methylthio-1H-tetrazole [CAS RN:
29515-99-9]
5-Benzylthio-1H-tetrazole [CAS RN: 21871-47-6]
5-Nitrophenyl-1H-tetrazole
4,5-Dicyanoimidazole [CAS RN: 1122-28-7]
|
| SALES
SPECIFICATION |
|
APPEARANCE
|
white
to off-white crystalline powder |
|
ASSAY
|
98.0%
min
|
|
MELTING
POINT
|
155
-158 C |
| TRANSPORTATION |
| PACKING |
10kgs
in drum
|
| HAZARD
CLASS |
1.1
(Packing Group: I) |
| UN
NO. |
0504 |
| REMARKS |
| Hazard Symbols: O, Risk Phrases: 5/8, Safety Phrases:
|