Thiazole is a
heterocyclic organic compound that has a five-member ring molecular structure,
C3H3NS, containing three
carbon atoms, one sulphur atom, and one nitrogen atom. It is a clear to
yellowish liquid with a pyridine like odor. It is soluble in alcohol and ether
and slightly soluble in water. It is parent material for numerous of chemical
compounds including sulfur drugs, biocides, fungicides, dyes, chemical reaction
accelerators. Thiazole dyes contain the color radicals of =C=N- and -S-C= which
decide colors to a compound . Azo dyes contain -N=N- radical. Thiazole dyes are
useful in dying cotton. Benzothiazole is a thiazole fused to benzene ring.
Benzothiazole derivatives are important in the industry of dyes, photographic
chemicals, sulfa drugs and rubber. Thiabendazole, a substituted derivative of
benzimidazole, is used as broad-spectrum anthelmintic and presevative. Some
thiazole derivatives, belong to a class of cyclic sulfur organo products
containing sulfur atom (S) and often oxygen (O), nitrogen (N), hydrogen (H), as
well as other elements, can find application for making biological activitive
agents such as antiviral, antibacterial, antifungal , antituberculous, antbody
and antifungal agents. Thiazole and its derivatives are also used as thiol
flavouring substances.Thiadiazole contains the
five-membered diunsaturated ring structure composed of
two nitrogen atoms and one sulfur atom. Thiadiazole
and its derivatives are used for biological activities
such as antiviral, antibacterial, antifungal and antituberculous. Benzothiadiazole,
fused to benzene ring with
two nitrogen atoms at 1,3 position and one sulfur atom at 2 position in the
five-membered ring, is known as an inducer of systemic resistance to diseases
rather than direct antifungal or antibacterial activities.