2-FLUOROPYRIDINE

PYRIDINE, also called azabenzene and azine, is a heterocyclic aromatic tertiary amine characterized by a six-membered ring structure composed of five carbon atoms and a nitrogen which rplace one carbon-hydrogen unit in the benzene ring. The simplest member of the pyridine family is pyridine itself. It is colorless, flammable, toxic liquid with a unpleasant odor, miscible with water and with most organic solvents, boils at 115 C. Its aqueous solution is slightly alkaline. It is incompatible and reactive with strong oxidizers and strong acids, and reacts violently with chlorosulfonic acid, maleic anhydride, oleum, perchromates, b-propiolactone, formamide, chromium trioxide, and sulfuric acid. Liquid pyridine easily evaporates into the air. If it is released to the air, it may take several months to years until it breaks down into other compounds. It is made from crude coal tar or from other chemicals based on acetaldehyde and ammonia. It is used as a solvent as a denaturant for alcohol and is added to ethyl alcohol to make it unfit for drinking. It is a starting material in the synthesis of other compounds used as an intermediate in making insecticides, herbicides, medicines, vitamins, food flavorings, dyes, rubber chemiclas, and adhesives such as sulfapyridine, pyribenzamine, pyrilamine and piperidine. It is also used as a denaturant for antifreeze mixtures, as a dyeing assistant in textiles and in fungicides. Compounds not made from pyridine but containing its ring structure include niacin and pyridoxal; isoniazid, nicotine and several other nitrogenous plant products. Pyridine derivatives are used as solvents and organic intermediates for pesticides products, pharmaceuticals, waterproofings, paints, explosives, dyestuffs, rubber chemicals, vitamins, sulfa drugs and disinfectants. 2-Fluoropyridine is used as an intermediate for manufacturing synthetic organic, pharmaceuticals (antihistamine drug, pheniramine, the antiarrhythmic, disopyramide) and agrochemicals (fungicides, herbicides). It is used as a catalyst for phase transfer and and a intermediate in the manufacture of pyrithione-based biocides.

2-FLUOROPYRIDINE
PRODUCT IDENTIFICATION
CAS NO.	372-48-5
EINECS NO.	206-757-5
FORMULA	C₅H₄FN
MOL WT.	97.09
H.S. CODE
TOXICITY
SYNONYMS	alpha-Fluoropyridine; o-Fluoropyridine;
SMILES
CLASSIFICATION
PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE	clear liquid
MELTING POINT
BOILING POINT	124 - 126 C
SPECIFIC GRAVITY	1.128 - 1.130
SOLUBILITY IN WATER
pH
VAPOR DENSITY	3.3
AUTOIGNITION
NFPA RATINGS	Health: 1 Flammability: 3 Reactivity: 1
REFRACTIVE INDEX	1.4680
FLASH POINT	28 C
STABILITY	Stable under ordinary conditions.
GENERAL DESCRIPTION AND APPLICATIONS
PYRIDINE, also called azabenzene and azine, is a heterocyclic aromatic tertiary amine characterized by a six-membered ring structure composed of five carbon atoms and a nitrogen which rplace one carbon-hydrogen unit in the benzene ring. The simplest member of the pyridine family is pyridine itself. It is colorless, flammable, toxic liquid with a unpleasant odor, miscible with water and with most organic solvents, boils at 115 C. Its aqueous solution is slightly alkaline. It is incompatible and reactive with strong oxidizers and strong acids, and reacts violently with chlorosulfonic acid, maleic anhydride, oleum, perchromates, b-propiolactone, formamide, chromium trioxide, and sulfuric acid. Liquid pyridine easily evaporates into the air. If it is released to the air, it may take several months to years until it breaks down into other compounds. It is made from crude coal tar or from other chemicals based on acetaldehyde and ammonia. It is used as a solvent as a denaturant for alcohol and is added to ethyl alcohol to make it unfit for drinking. It is a starting material in the synthesis of other compounds used as an intermediate in making insecticides, herbicides, medicines, vitamins, food flavorings, dyes, rubber chemiclas, and adhesives such as sulfapyridine, pyribenzamine, pyrilamine and piperidine. It is also used as a denaturant for antifreeze mixtures, as a dyeing assistant in textiles and in fungicides. Compounds not made from pyridine but containing its ring structure include niacin and pyridoxal; isoniazid, nicotine and several other nitrogenous plant products. Pyridine derivatives are used as solvents and organic intermediates for pesticides products, pharmaceuticals, waterproofings, paints, explosives, dyestuffs, rubber chemicals, vitamins, sulfa drugs and disinfectants. 2-Fluoropyridine is used as an intermediate for manufacturing synthetic organic, pharmaceuticals (antihistamine drug, pheniramine, the antiarrhythmic, disopyramide) and agrochemicals (fungicides, herbicides). It is used as a catalyst for phase transfer and and a intermediate in the manufacture of pyrithione-based biocides.
SALES SPECIFICATION
APPEARANCE	clear liquid
ASSAY	98.0% min
MOISTURE	0.1% max
TRANSPORTATION
PACKING	200kgs in drum
HAZARD CLASS	3 (Packing Group: III)
UN NO.	1993
OTHER INFORMATION
`Hazard Symbols: XN F, Risk Phrases:` 10-36/37/38`, Safety Phrases: 9-`16-23-26-36-37-45