2-METHYLPIPERAZINE

PRODUCT IDENTIFICATION
CAS NO. 109-07-9

2-METHYLPIPERAZINE

EINECS NO. 203-644-2
FORMULA C5H12N2
MOL WT. 100.16

H.S. CODE

 

TOXICITY

 Oral rat LD50: 2030 mg/kg
SYNONYMS

2-Methyl-1,,4-Piperazine;

2-Methylpiperazin (German); 2-Metilpiperazina (Spanish); 2-Méthylpipérazine (French);
SMILES

 

CLASSIFICATION

  

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE 
white crystal
MELTING POINT 65 - 67 C
BOILING POINT 155 C
SPECIFIC GRAVITY  
SOLUBILITY IN WATER Easily soluble
pH  
VAPOR DENSITY

 

AUTOIGNITION

 

NFPA RATINGS Health: 2 ; Flammability: 2 ; Reactivity: 0

REFRACTIVE INDEX

  
FLASH POINT

63 C

STABILITY

Stable under ordinary conditions. Hydroscopic.

GENERAL DESCRIPTION & APPLICATIONS
Piperazine is a heterocyclic compound containing four carbon atoms and two of nitrogen at 1,4 position ( als called 1,4-hexahydropyrazine). It is a deliquescent crystalline compound melting at 105 C; soluble in water, alcohol, glycerol, and glycols. It is used as a main ingredient of anthelmintics used to treat intestinal roundworms (ascariasis) infection in human and  poultry and to treat pinworms (enterobiasis; oxyuriasis) by altering cell membrane permeability and causing hyperpolarization of the membrane. Piperazine is a main moiety in psychoactive drugs. Certain piperazine derivatives are suspected of ecstasy substitutes. Benzylpiperazine is bannaed in many countries. Benzylpiperazine  has been used as a anthelmintic (antiparastic effect). Nitrogen in piperazine ring plays an important role in biological research and drug manufacturing industry including the preparation of anthelmintic, antiallergenic, antibacterial, antihistamic, antiemetic and antimigraine agents. The piperazine ring and piperazine derivatives are important cyclic components in industrial field as raw materials for hardener of epoxy resins, corrosion inhibitors, insecticides, accelerators for rubber, urethane catalysts and antioxidants. N-(2-Hydroxyethyl)piperazine is used in the synthesis of drugs like quinolone class antibiotics, agrochemicals and other chemical compounds.
SALES SPECIFICATION
APPEARANCE 
white crystal

PURITY

99.0% min

WATER

 0.5% max

INDIVIDUAL IMPURITY

0.5% max
TRANSPORTATION
PACKING
25kgs in fiber drum
HAZARD CLASS 8 (Packing Group: III)
UN NO. 3263
OTHER INFORMATION
Hazard Symbols: XI, Risk Phrases: 36/37/38, Safety Phrases: 24/25