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4,4'-DIFLUOROBENZHYDROL | ||
PRODUCT IDENTIFICATION |
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CAS NO. | 365-24-2 |
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EINECS NO. | 206-671-8 | |
FORMULA | C13H10F2O | |
MOL WT. | 219.99 | |
H.S. CODE |
2907.29 | |
TOXICITY |
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SMILES |
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SYNONYMS | Bis(4-fluorophenyl)methanol; | |
SMILES |
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CLASSIFICATION |
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PHYSICAL AND CHEMICAL PROPERTIES |
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PHYSICAL STATE | off-white crystals | |
MELTING POINT | 46 - 49 C | |
BOILING POINT |
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SPECIFIC GRAVITY | ||
SOLUBILITY IN WATER | ||
pH | ||
VAPOR DENSITY |
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AUTOIGNITION |
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NFPA RATINGS |
Health: 1; Flammability: 0; Instability: 0 | |
REFRACTIVE INDEX |
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FLASH POINT | > 110 C | |
STABILITY |
Stable under ordinary conditions |
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APPLICATIONS |
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Benzhydrol is used as an intermediate of pharmaceuticals (including antihistamines), agrochemicals and other organic compounds. It is used as a fixative in perfumery and as a terminating group in polymerizations. Benzhydyl is a skeleton for Histamine H1 antagonist which an ethylamine group is attached to a diphenyl metahne structure. Common examples are diphenhydramine, diphenidol and phenyltoloxamine. Benzhydryl compounds contain two benzene rings which substitute hydrogen atoms in the methane molecule. This structure does not allow the fusion of benzene ring. This nomenclature system is particularly useful to describe the groups attached to the benzene rings and the additional substituents on the methane. The benzhydryl structure features as the motif for modified fibers, polymers and curing agents. The benzhydryl motif is a fundamental component also in drugs such antihistamines, antihypertensive agents and antiallergenic agents. Diphenylmethane structure is a moiety of pesticides such as hexachlorophene and (CAS RN: 70-30-4) and dichlorophen (CAS RN: 97-23-4). The term "trityl " refers to a triphenylmethanyl compound in which three phenyl rings are bonded to a single carbon. Trityl anion stabilized by extensive delocalization over three phenyl rings absorbs the visible region of the spectrum and originates brilliant and fluorescent red to violet colors. Triphenylmethane is the basic skeleton of many dyes. |
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SALES SPECIFICATION | ||
APPEARANCE |
off-white crystals | |
ASSAY |
99.0% min |
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MELTING POINT | 46 - 48 C | |
LOSS ON DRYING |
0.5% max |
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TRANSPORTATION | ||
PACKING |
200kgs
in drum
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HAZARD CLASS | Not regulated | |
UN NO. | ||
OTHER INFORMATION | ||
Hazard Symbols: n/a, Risk Phrases: n/a, Safety Phrases: 28A/37/37/45 |
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