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4-(4-CHLOROPHENYL)-4-HYDROXYPIPERIDINE | ||
PRODUCT IDENTIFICATION |
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CAS NO. | 39512-49-7 |
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EINECS NO. | 254-479-8 | |
FORMULA | C11H14ClNO | |
MOL WT. | 211.69 | |
H.S. CODE |
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TOXICITY |
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SYNONYMS | 4-(4-chlorophenyl)-4-piperidinol; haloperidol metabolite I; | |
4-(4-Chlorophenyl)piperidin-4-ol; | ||
SMILES |
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CLASSIFICATION |
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PHYSICAL AND CHEMICAL PROPERTIES |
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PHYSICAL STATE | white to beige powder | |
MELTING POINT | 138 - 141 C | |
BOILING POINT |
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SPECIFIC GRAVITY | ||
SOLUBILITY IN WATER | 350mg/l at 20 C | |
pH | ||
VAPOR DENSITY |
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AUTOIGNITION |
400 C | |
NFPA RATINGS |
Health: 1; Flammability: ; Reactivity: 0 | |
REFRACTIVE INDEX |
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FLASH POINT |
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STABILITY |
Stable under ordinary conditions | |
APPLICATIONS |
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Piperidine, hexahydropyridine, is a family of heterocyclic organic compound derived from pyridine through hydrogenation. It has one nitrogen atom in the cycle. It is a clear liquid with pepper-like aroma. It boils at 106 C, soluble in water, alcohol, and ether. The major application of piperidine is for the production of Dipiperidinyl dithium tetrasulfide used as a rubber vulcanization accelerator. In pharmaceutical synthesis industry, it is used as a special solvent and a protecting group for peptide synthesis. Piperidine derivative compounds are used as intermediate to make crystal derivative of aromatic nitrogen compounds containing nuclear halogen atoms. Ring system compounds with nitrogen which have basic property play important roles as cyclic component in industrial field such as raw materials for hardener of epoxy resins, corrosion inhibitors, insecticides, accelerators for rubber, urethane catalysts, antioxidants and as a catalyst for silicone esters. They are used in manufacturing pharmaceuticals. 4-(4-Chlorophenyl)-4-hydroxypiperidine is used as an intermediate for the synthesis of pharmaceuticals such as haloperidol (neuroleptic drug used to treat patients with psychotic illnesses, extreme agitation, or Tourette's syndrome) and loperamide (an opioid that slows down movements of the gut and is used to treat acute diarrhoea) |
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SALES SPECIFICATION | ||
APPEARANCE |
white to beige powder | |
ASSAY |
99.0% min |
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MOISTURE |
0.5% max | |
TRANSPORTATION | ||
PACKING | 25kgs
in fiber drum | |
HAZARD CLASS | Not regulated | |
UN NO. | ||
OTHER INFORMATION | ||
Hazard Symbols: n/a, Risk Phrases: n/a, Safety Phrases: 28A/37/38/45 |
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