| CAS
NO. |
136-77-6 |
|
| EINECS
NO. |
205-257-4 |
| FORMULA |
C12H18O2 |
| MOL
WT. |
194.27 |
|
H.S.
CODE
|
|
|
TOXICITY
|
Oral rat LD50: 550 mg/kg |
| SYNONYMS |
4-Hexyl-1,3-dihydroxybenzene;
|
| 4-Hexyl-1,3-benzenediol; 4-Hexylresorcinol; 4-n-hexylresorcinol; Ascaryl; crystoids anthelmintic; Gelovermin; Caprokol; Hexylresorcinol; 4-Hexylresorcin (Dutch); 4-hexilresorcinol
(Spanish); 4-hexylrésorcinol
(French); 4-hexylresorcine;
|
| DERIVATION |
|
|
CLASSIFICATION
|
|
|
PHYSICAL
AND CHEMICAL PROPERTIES
|
| PHYSICAL
STATE |
White
to off-white crystals
|
| MELTING
POINT |
65 - 67 C |
| BOILING
POINT |
333
C |
| SPECIFIC
GRAVITY |
|
| SOLUBILITY
IN WATER |
<
0.1 g/100ml (soluble in alcohol and ether) |
| pH |
|
| VAPOR
DENSITY |
|
|
AUTOIGNITION
|
|
|
NFPA
RATINGS
|
Health:
2; Flammability: 0; Reactivity: 0 |
|
REFRACTIVE
INDEX
|
|
| FLASH
POINT |
|
| STABILITY |
Stable
under ordinary conditions. |
| GENERAL
DESCRIPTION AND APPLICATIONS |
| There
are three isomeric compounds of dihydroxybenzene molecule
structure, which all have traditional names respectively.
The ortho (1,2) isomer is called catechol (Also known
as catechin; pyrocatechol; pyrocatechuic acid), which
forms clear crystals used as a photographic developer
in solution and as a starting material to produce synthetic
catecholamines which have important physiological effects
as neurotransmitters and hormonesany (such as epinephrine,
adrenaline, norepinephrine, and dopamine). The meta
(1,3) isomer is resorcinol (also known as resorcin),
which forms clear needle crystals used in the production
of diazo dyes and plasticizers. It is produced by sulfonating
benzene with fuming sulfuric acid and fusing the resulting
benzenedisulfonic acid with caustic soda. Resorcinol
is used in resins as an UV absorber. It is used in manufacturing
fluorescent and leather dyes and adhesives. Reaction
with formaldehyde produces resins (resorcinol formaldehyde
resins) used to make rayon and nylon. It is used as
a pharmaceutical to treat acne and other greasy skin
conditions in combination with other acne treatments
such as sulfur. It is used as an anti-dandruff agent
in shampoo and sunscreen cosmetics. It is also used
as a chemical intermediate to synthesis pharmaceuticals
and other organic compounds. The para (1,4) isomer is
hydroquinone (also known as quinol), which forms clear
prisms used as a photographic reducer and developer
(except in color film). It is formed in large quantities
by chemical reduction of benzoquinone. This compound
is a general-purpose inhibitor, stabilizer, antioxidant,
and intermediate. One of the major uses of hydroquinone
is as an intermediate to make other inhibitors, stabilizers,
antioxidants, agricultural chemicals, and dyes. Resorcinol
and its derivatives are used in resins as UV absorbers.
They are used in manufacturing fluorescent and leather
dyes and adhesives (resorcinol formaldehyde resins).
They are used as pharmaceuticals to treat acne and other
greasy skin conditions in combination with other acne
treatments such as sulfur. They are used as an anti-dandruff
agent in shampoo and sunscreen cosmetics.
4-Hexylresorcinol,
insoluble in water, soluble in alcohol and ether,
is used as an anthelmintic and antiseptic agent for
mouthwashes and skin wound cleansers and
anti-browning agent in foods.
|
| SALES
SPECIFICATION |
|
APPEARANCE
|
White
to off-white crystals
|
|
ASSAY
|
98.0
- 102.0% |
| ASH |
0.2%
max
|
| TRANSPORTATION |
| PACKING |
20kgs
in fiber drum
|
| HAZARD
CLASS |
|
| UN
NO. |
|
| OTHER
INFORMATION |
| Hazard Symbols: XN, Risk Phrases: 22/36/38/50, Safety
Phrases: 24/25-28A-37-45 |
| GENERAL DESCRIPTION OF ANTISEPTIC
AGENT |
Antiseptic agent
is a substance which kills or inhibits the growth of disease-causing bacteria
and other microorganisms. It is essentially nontoxic to to be applied to the
skin or mucous membranes. (Disinfectant including cresol, bleaching powder, and
phenol is in general toxic to cells of the body). Common antiseptic agents are
Benzalkonium Chloride, Cetrimide, Chlorhexidine, Hexachlorophene, Iodine
Compounds, Mercury Compounds (Thimerosol), Alcohol and Hydrogen Peroxide,
Hexamine Hippurate, Triclosan, Cetylpyridinium Chloride, And Dequalinium. Other
substances which can be used for antiseptic purpose include Boric acid and
volatile oils such as Methyl Salicylate.
Hexachlorophene and Benzalkonium
Chloride are used primarily in hand or face washes. Benzalkonium Chloride must
not be applied to areas which have not been fully rinsed as it is inactivated by
organic compounds. Benzalkonium application many include disinfecting
instruments and preservativing drugs in low concentration form.
Iodine
compounds have the widest spectrum of antiinfectives against bacteria, fungi,
spores, protozoa, viruses, and yeasts. Aqueous iodine are less effective than
alcoholic solutions, but alcoholic component is drying and irritating to
abraided skin. Povidone iodine is convenient to use as it is less irritating,
but not as effective.
Chlorhexidine is used as a safe antiseptic or
disinfectant to apply to prevent body infection and in oral rinses for treating
sore gums and mouth ulcers and preventing plaque on teeth. It is used in the
form of acetate, gluconate or hydrochloride, either alone or in combination with
others such as cetrimide.
Cetrimide is an antiseptic agent with detergent
properties. It has the wide spectrum of antiinfectives against bacteria and
fungi. It is used as an ingredient of shampoos for treating seborrhoea and
psoriasis. A very dilute solution can be applied topically for the relief of
sore gums.
Hippuric Acid, an amino acid glycine, is excreted from the body
and is used in urinary system drugs. Hexamine hippurates is helpful for
preventing and treating infections of the urinary system; it acts by being
transformed to formaldehyde.
Triclosan is a very popular antibacterial agent.
It is used in hospitals for cleansing and disinfecting the skin of patients and
surgeons. It is used in cosmetics, household goods and personal care products.
It is also used in plastics and textiles for antibacterial activity
purpose.
Cetylpyridinium chloride is used in oral rinses for cleaning mouth
and treating minor throat or mouth infections and teething problems.
Dequalinium chloride is antiinfectives against bacteria and fungi. It is
used in treating bacterial or fungal infections of mouth and throat.
|
PRICE
INFORMATION
|
|
