4-(HYDROXYPHENYL)ACETAMIDE

PRODUCT IDENTIFICATION
CAS NO. 17194-82-0

4-HYDROXYPHENYLACETAMIDE

EINECS NO. 241-235-0
FORMULA HOC6H4CH2CONH2
MOL WT. 151.17
H.S. CODE

2924.29

TOXICITY

SYNONYMS 4-Hydroxybenzeneacetamide;

2-(p-Hydroxyphenyl)acetamide; p-(Carbamoylmethyl)phenol; 4-Hydroxyphenylacetamide
SMILES  

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE Beige powder
MELTING POINT

176 C

BOILING POINT  
SPECIFIC GRAVITY

 

SOLUBILITY IN WATER Soluble
AUTOIGNITION  
NFPA RATINGS  
FLASH POINT  
STABILITY Stable under normal temperatures and conditions

GENERAL DESCRIPTION & APPLICATIONS
Phenylacetic acid is a white crystals with a disagreeable odor; boiling point 262 C; soluble in alcohol and ether. It serves as an ingredient in perfume to provide honey-like odor. It is found as a moiety in some alkaloids and plant hormones. It is formed as catabolite of phenylalanine. Substituted phenylacetic acid molecule at alpha position and phenylacetate esters can serve as a drug with a wide variety of effects including anticholinergic, muscarinic antagonist, antidote to cholinesterase inhibitors or toxins, cycloplegic and mydriatic. Phenylacetic acid is used to prepare a nonsteroidal antiinflammatory drug like diclofenac. It is used the manufacture of penicillin. Mandelic Acid, phenylglycollic acid, can be produced from phenylchloracetic acid.

4-(Hydroxyphenyl)acetamide is used as an intermediate for organic compounds and pharmaceuticals ( especially for Atenolol)
SALES SPECIFICATION

APPEARANCE

 White to beige powder
ASSAY

98.5% min

MELTING POINT

174 C min

LOSS ON DRYING

0.5% max

TRANSPORTATION
PACKING 25kgs in bag
HAZARD CLASS  
UN NO.  
REMARKS

Atenolol, chemically 4 -[2'-hydroxy-3'-[(1- methylethyl) amino] propoxy]- benzeneacetamide, is a cardioselective beta blocker used to control abnormal heart rhythms, to treat angina, and to reduce high blood pressure. Beta blocker is a drug blocking nerve impulses to special sites (beta receptors) in the cerebellum and reduces the rate of heartbeats and the force of heart contractions. Other beta blockers include acebutolol, betaxolol, bisoprolol, oxprenolol, propranolol, and sotalol.