4-METHYLBENZHYDROL

PRODUCT IDENTIFICATION

CAS NO. 1517-63-1

4-METHYLBENZHYDROL

EINECS NO. 216-171-1
FORMULA C14H14O
MOL WT. 198.26

H.S. CODE

2907.29

TOXICITY

 
SYNONYMS Phenyl-p-tolylcarbinol;
Benzhydryl alcohol, methyl ester;
SMILES

 

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE white crystals
MELTING POINT 50 - 54 C
BOILING POINT

 

SPECIFIC GRAVITY  
SOLUBILITY IN WATER  
pH  
VAPOR DENSITY

 

AUTOIGNITION

 

NFPA RATINGS

 

REFRACTIVE INDEX

 

FLASH POINT > 110 C
STABILITY

Stable under ordinary conditions

APPLICATIONS

Benzhydrol is used as an intermediate of pharmaceuticals (including antihistamines), agrochemicals and other organic compounds. It is used as a fixative in perfumery and as a terminating group in polymerizations. Benzhydyl is a skeleton for Histamine H1 antagonist which an ethylamine group is attached to a diphenyl structure. Common examples are diphenhydramine,diphenidol and phenyltoloxamine. Benzhydryl polymer-bound molecules are used as solid support for the synthesis of peptide, DNA, and certain alignment molecules.

Benzhydryl compounds contain two benzene rings which substitute hydrogen atoms in the methane molecule. This structure does not allow the fusion of benzene ring. This nomenclature system is particularly useful to describe the groups attached to the benzene rings and the additional substituents on the methane. The benzhydryl structure features as the motif for modified fibers, polymers and curing agents. The benzhydryl motif is a fundamental component also in drugs such antihistamines, antihypertensive agents and antiallergenic agents. Diphenylmethane structure is a moiety of pesticides such as hexachlorophene and (CAS RN: 70-30-4) and dichlorophen (CAS RN: 97-23-4). The term "trityl " refers to a triphenylmethanyl compound in which three phenyl rings are bonded to a single carbon. Trityl anion stabilized by extensive delocalization over three phenyl rings absorbs the visible region of the spectrum and originates brilliant and fluorescent red to violet colors.  Triphenylmethane is the basic skeleton of many dyes.
SALES SPECIFICATION

APPEARANCE

white crystals

ASSAY

98.0% min

MELTING POINT 50 - 54 C

LOSS ON DRYING

0.5% max

TRANSPORTATION
PACKING
200kgs in drum
HAZARD CLASS Not regulated
UN NO.  
OTHER INFORMATION
Hazard Symbols: n/a, Risk Phrases: n/a, Safety Phrases: 28A/37/37/45