|
5-METHYLURIDINE | |||
PRODUCT IDENTIFICATION |
|||
CAS NO. | 1463-10-1 |
|
|
EINECS NO. | 215-973-9 | ||
FORMULA | C10H14N2O6 | ||
MOL WT. | 258.23 | ||
H.S. CODE |
2933.90.7500 | ||
TOXICITY |
|||
SYNONYMS | Ribosylthymine; m5U; Thymine riboside; | ||
5-Methyl-1-(ет-L-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione; |
|||
1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan- 2-yl]-5-methylpyrimidine- 2,4-dione; Ribothymidine; Other RN:849658-09-9 |
|||
SMILES | O=c1[nH]c(=O)n([C@@H]2O[C@H](CO)[C@H](O)[C@H]2O)cc1C | ||
CLASSIFICATION |
Pyrimidinedione, Riboside, Nucleoside |
||
EXTRA NOTES |
|||
PHYSICAL AND CHEMICAL PROPERTIES |
|||
PHYSICAL STATE |
white to off-white crystalline powder |
||
MELTING POINT |
183 - 187 C |
||
BOILING POINT | |||
SPECIFIC GRAVITY | |||
SOLUBILITY IN WATER | |||
pH | |||
VAPOR DENSITY |
|
||
AUTOIGNITION |
|
||
NFPA RATINGS | |||
REFRACTIVE INDEX |
|||
FLASH POINT | |||
STABILITY |
Stable under ordinary conditions |
||
EXTERNAL LINKS & GENERAL DESCRIPTION |
|||
Drug Information Portal (U.S. National Library of Medicine) - Thymine riboside PubChem Compound Summary - Ribothymidine Drug Bank - 5-Methyluridine KEGG (Kyoto Encyclopedia of Genes and Genomes) - Ribothymidine http://www.ebi.ac.uk/chebi/ - Ribothymidine Local:
Thymine is a pyrimidine base, occurring condensed with deoxyribose to form the nucleoside deoxythymidine in animal cells. Thymidine is significant because of its involvement in the biosynthesis of DNA and in the preservation and transfer of genetic information. It was thought that there is no thymine in ribonucleic acid (RNA); the thymine nucleotides contain only deoxyribose. However, It is now known that thymine, produced from uracil by post-transcriptional methylation, occurs as a rare base in rRNAs and tRNAs. When N1 is linked to the C1 of ribose, thymine forms a pyrimidine nucleoside called thymidines which are phosphorylated with from one to three phosphoric acid groups to form the three nucleotides; thymidine monophosphate(TMP), thymidine diphosphate(TDP), and thymidine triphosphate (TTP) respectively. When N1 is linked to the C1 of deoxyribose, deoxy nucleosides and nucleotides are formed from thymine and deoxyribose; deoxythymine monophosphate (dTMP), deoxythymine diphosphate (dTDP), and deoxythymine triphosphate (dTTP). TTP is involved in the formation of adenosine triphosphate (ATP) as a donator of phosphate groups to adenosine diphosphate (ADP).
Chemically modified nucleotides substituted or attached by special chemical groups or elements are studied and used to inactivate the normal biological operation in the living organism and the function of important enzymes. |
|||
SALES SPECIFICATION | |||
APPEARANCE |
fine off-white crystalline powder |
||
ASSAY |
98.0 - 102.0 % |
||
MELTING POINT |
183 - 187 C |
||
TRANSPORTATION | |||
PACKING |
|
||
HAZARD CLASS | |||
UN NO. | |||
OTHER INFORMATION | |||
Hazard Symbols: n/a, Risk Phrases: 36/37/38, Safety Phrases: 22-24/25 | |||
PRICE INFORMATION | |||
|
|