6-CHLOROQUINOLINE

PRODUCT IDENTIFICATION
CAS NO. 612-57-7

6-CHLOROQUINOLINE
EINECS NO.

210-314-1
FORMULA C9H6ClN
MOL WT. 163.61

H.S. CODE

  

TOXICITY

  
SYNONYMS 6-Chlorobenzopyridine; 6-Chloroquinoléine (French);
6-Chlorchinolin (German); 6-Cloroquinolina (Spanish);
SMILES

 

CLASSIFICATION

  

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE light yellow crystals
MELTING POINT 40 - 43 C
BOILING POINT 126 - 127 C at 10 hPa
SPECIFIC GRAVITY

 
SOLUBILITY IN WATER  
pH  
VAPOR DENSITY

 

REFRACTIVE INDEX

 

NFPA RATINGS

 Health: 2; Flammability: 1; Reactivity: 0

AUTOIGNITION

 

FLASH POINT

>110 C
STABILITY Stable under normal conditions
GENERAL DESCRIPTION OF QUINOLINE and APPLICATIONS
Quinoline, 1-azanaphthalene, is an aromatic nitrogen compound characterized by a double-ring structure contains a benzene fused to pyridine at two adjacent carbon atoms. (Pyridine is a ring structure compound of five carbon atoms with a nitrogen atom). Quinoline itself is the simplest member of the quinoline. It is a hygroscopic, yellowish oily liquid; slightly soluble in water, soluble alcohol, ether, carbon disulfide and readily in many organic solvents. It can be obtained by the distillation of coal tar. Quinoline can be prepared from aniline with acrolein under heated sulfuric acid (Skraup synthesis). Various quinoline compounds can be prepared by Skraup synthesis series of different oxidizing agents. Isoquinoline differs from quinoline in nitrogen position (at 2). Quinoline family compounds are widely used as a parent compound to make drugs (especially anti-malarial medicines), fungicides, biocides, alkaloids, dyes, rubber chemicals and flavoring agents. They have antiseptic, antipyretic, and antiperiodic properties. They are also used as catalyst, corrosion inhibitor, preservative, and as solvent for resins and terpenes. They are used in transition-metal complex catalyst chemistry for uniform polymerization and luminescence chemistry. They are used as antifoaming agent in refinery field. Quinaldine, 2-methylquinoline, is used as an anti-malaria and preparing other anti-malaria drugs. It is used in manufacturing oil soluble dyes, food colorants, pharmaceuticals, pH indicators and other organic compounds. Quinaldic Acid is a carboxylic acid substituted quinoline at 2 position, a catabolite of tryptophan (aromatic side chain amino acid). Quinazoline, diazanaphthalene at 1,3 positions, is used as a chemical intermediate for making medicines and other organic compounds. It is a fundamental structure in some antihypertensive agents such as prazosin and doxazosin which are peripheral vasodilator. Quinoxaline, diazanaphthalene at 1,4 positions, is used as a chemical intermediate for making fungicides and other organic compounds.
SALES SPECIFICATION

APPEARANCE

 light yellow crystals

CONTENT

98.0% min

MELTING POINT

 40 - 43 C
TRANSPORTATION
PACKING
25kgs in  fiber drum
HAZARD CLASS Not regulated
UN NO.  
OTHER INFORMATION
Hazard Symbols: XI, Risk Phrases: 36/37/38, Safety Phrases: 26-36-37-45