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CHOLESTEROL | ||
PRODUCT IDENTIFICATION |
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CAS NO. | 57-88-5 |
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EINECS NO. | 200-353-2 | |
FORMULA | C27H46O | |
MOL WT. | 386.66 | |
H.S. CODE |
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TOXICITY |
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SYNONYMS | 3beta-Hydroxy-5-cholestene | |
3beta-Cholest-5-en-3-ol (-)-Cholesterol Cholest-5-en-3beta-ol Cholesterin Cholesteryl alcohol Provitamin D 3beta-Hydroxycholest-5-ene 5:6-Cholesten-3beta-ol 5-Cholesten-3beta-ol Cholesterine Cholesterolum | ||
SMILES |
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CLASSIFICATION |
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PHYSICAL AND CHEMICAL PROPERTIES |
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PHYSICAL STATE |
white crystalline
solid | |
MELTING POINT | 140 C | |
BOILING POINT |
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SPECIFIC GRAVITY | 1.06 - 1.07 | |
SOLUBILITY IN WATER | 0.2% | |
pH |   | |
VAPOR DENSITY |
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AUTOIGNITION |
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NFPA RATINGS |
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REFRACTIVE INDEX |
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FLASH POINT |
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STABILITY |
Stable under ordinary conditions. | |
GENERAL DESCRIPTION & APPLICATIONS |
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Cholesterol is a steroid alcohol that is essentially insoluble in aqueous solutions. In mammals, it is normally solubilized by its association with other lipids, such as phospholipids or bile acids thus, most cholesterol is found in cell membranes, plasma lipoproteins, and bile. Cholesterol can be esterified with a fatty acid to form cholesteryl esters. The latter form discrete lipid droplets in cells, especially in cells of steroidogenic tissues, and in the lipid core of low-density lipoproteins in the blood. Cholesterol is a fatty lipid sparingly insoluble in water but soluble in a number of organic solvents. It is the most common sterol of eukaryotes which a key constituent of cell membranes and works as the precursor of bile acids, cholecalciferol (vitamin D)  and steroid hormones including cortisol, cortisone,  aldosterone and sex hormone progesterone in vertebrates. Cholesterol is used as an emulsifying agent in pharmaceuticals. The most cholesterols are synthesized by the liver and other tissues include the adrenal glands and reproductive organs. Some cholesterol  is absorbed from dietary sources. The largest concentration of cholesterol is in the myelin sheath that surrounds nerves and in the plasma membrane that surrounds all cells in vertebrates (25% of brain lipid is cholesterol). Cholesterol can be esterified with a fatty acid to form cholesteryl esters which form discrete lipid droplets in cells, especially in cells of steroidogenic tissues, and in the lipid core of low-density lipoproteins in the blood. The collection on the walls of arteries interferes with the flow of blood. The High level of cholesterol in the blood is a major risk factor for coronary heart diseases. Cholesteric materials are liquid crystals of mesomorphic phase in which molecules are parallel to each other within the plane of a layer, but the direction is oriented in loose parallel lines to form a helix through the layers. Cholesteric materials are temperature sensitive and have color changing ability upon temperature. Not only emulsifying and humectant properties but also liquid crystal properties of cholesterol and its derivatives (salts and esters) make them useful in the commercial applications of cosmetics and pharmaceuticals. | ||
SALES SPECIFICATION | ||
APPEARANCE |
white crystalline
solid |
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ASSAY |
98.0% min |
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LOSS ON DRYING |
0.5% max |
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MELTING POINT | 135 - 140 C | |
TRANSPORTATION | ||
PACKING | 25kgs in fiber drum | |
HAZARD CLASS |   | |
UN NO. |   | |
OTHER INFORMATION | ||
Hazard Symbols: , Risk Phrases: , Safety Phrases: 22-24/25 | ||
CAS # OF CHOLESTERYL COMPOUNDS | ||
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