PRODUCT IDENTIFICATION
H.S. CODE
TOXICITY
c12c(c(c(c3ccc(O)cc3)co1)=O)c(cc(c2)O)O
CLASSIFICATION
Anticarcinogenic, Antineoplastic, Non-Steroidal Estrogen, Hormone Antagonist, Phytoestrogen, Protein Kinase Inhibitor
EXTRA NOTES
PHYSICAL AND CHEMICAL PROPERTIES
Soluble in DMSO, ethanol
AUTOIGNITION
NFPA RATINGS
REFRACTIVE INDEX
Stable under ordinary conditions.
EXTERNAL LINKS & GENERAL DESCRIPTION
Wikipedia Linking - Genistein
Google Scholar Search - Genistein
Drug Information Portal (U.S. National Library of Medicine) - Genistein
PubChem Compound Summary - Genistein
Drug Bank - Genistein
KEGG (Kyoto Encyclopedia of Genes and Genomes) - Genistein
http://www.ebi.ac.uk/ - Genistein
http://www.ncbi.nlm.nih.gov/ - Genistein
Local:
Flavonoid is any
member of a class of widely distributed biological natural products containing
aromatic heterocyclic skeleton of flavan (2-Phenylbenzopyran) but no nitrogen in
plants. Generally, flavonoids are biological pigments providing colours from red
to blue in flowers, fruit and leaves. Besides their coloring in plants,
flavonoids have important roles in the growth and development of plants;
protection against UV-B radiation; forming antifungal barriers; antimicrobial,
insecticidal and oestrogenic activities; plant reproduction. Flavonoids also
exhibit a wide range of biological properties including anti-microbial,
insecticidal and oestrogenic activities. Flavonoids are usually classified
into main 6 subgroups as below plus flavans,
neoflavonoids, flavonols, aurons, catechins according to the structural patterns.
- Flavonols (Hydroxy derivatives of flavone): Fisetin, Galangin, Kaempferide, Kaempferol, Morin, Myricetin, Myricitrin, Quercetin, Quercetrin, Rhamnetin, Robinin, Rutin, Spirenoside
- Flavones (skeleton: 2-phenylchromen-4-one): Apigenin, Baicalein, Chrysin, Diosmetin, Diosmin, Flavone, Luteolin, Rpoifolin,Tangeretin, Techtochrysin, Rhamnazin, Nobiletin, Natsudaidain.
- Isoflavones (skeleton: 3-phenylchromen-4-one): Daidzin, Genistein, Irilone, Luteone, Prunetin, Pratensein,
- Flavonones (derivation by reduction of the 2(3) C=C bond): Eriodictyol, Hesperidin, Hesperetin, Likvirtin, Naringin; Naringenin; Pinocembrin
- Flavanols (derivation by reduction of the keto group):(+)-Catechin, (+)-Gallocatechin, (-)-Epicatechin (EC), (-)-Epigallocatechin (EGC), (-)-Epicatechin 3-gallate (ECG), (-)-Epigallocatechin 3-gallate (EGCG), Theaflavin, Theaflavin 3-gallate, Theaflavin 3'-gallate, Theaflavin 3,3' digallate, Thearubigins
- Anthocyanidins (aglycones of the glycoside anthocyanins): Apigeninidin, Cyanidin, Delphinidin, Diosmetinidin, Guibourtinidin, Fisetinidin, Luteolinidin, Malvidin, Pelargonidin, Peonidin, Robinetinidin, Tricetinidin, Capensinidin, Petunidin, Europinidin, Aurentinidin, Columnidin, 5-Desoxy-malvidin, 5-Desoxy-peonidin, Hirsutinidin, Rosinidin
Genistein, found in soy products mostly, is known as the inhibitor of tyrosine protein kinases. The chemical structure is similar to that of estrogen and interfere with the metabolic action of estrogen. It prevents from hormone-related disorders such as breast cancer and prostate cancers. It is know as the inhibitor of hormone-related disorders, antioxidant, and as immune system enhancer.
APPEARANCE
ASSAY
1.0% max
117 - 119 C
RESIDUE ON IGNITION
0.2% max
HEAVY METALS
10ppm max
HAZARD OVERVIEW
Toxic by ingestion
GHS
Warning
PICTOGRAMS
HAZARD STATEMENTS
H302
P STATEMENTS
RIS PHRASES
36/38
SAFETY PHRASES
24-26