GLUTARALDEHYDE SOLUTION

PRODUCT IDENTIFICATION

CAS NO. 111-30-8

GLUTARALDEHYDE

EINECS NO. 203-856-5
FORMULA OHC(CH2)3CHO
MOL WT. 100.12

H.S. CODE

2912.19.5000

TOXICITY

Oral rat LD50: > 90 ml/kg
SYNONYMS Glutaric acid dialdehyde; Glutardialdehyde; Glutaral;
1,3-Diformylpropane; 1,5-Pentanedial; 1,5-Pentanedione; Glutaric aldehyde; Glutarol; Gluteraldehyde; Pentanedial; Sonacide; Aldehyd glutarowy; Aldesan; Ucarcide; Other RN: 37245-61-7, 79215-57-9, 107950-89-0
SMILES C(CC=O)CC=O

CLASSIFICATION

Disinfectant, Anti-Infective agent, Fixative

EXTRA NOTES

EPA Pesticide Chemical Code 043901
One of the protein cross-linking reagents that is used as a disinfectant for sterilization of heat-sensitive equipment and as a laboratory reagent, especially as a fixative. 

PHYSICAL AND CHEMICAL PROPERTIES (50% SOLUTION)

PHYSICAL STATE Clear to yellowish liquid
MELTING POINT -14 C
BOILING POINT 187 C
SPECIFIC GRAVITY  
SOLUBILITY IN WATER soluble
SOLVENT SOLUBILITY Soluble in alcohol
pH 3.2 - 4.2
VAPOR DENSITY

 

log P -0.18 (Octanol-water)
VAPOR PRESSURE 0.6 (mmHg at 25 C)
HENRY LAW CONSTANT 1.10E-07 (atm-m3/mole at 25 C)
OH RATE CONSTANT 2.38E-11 (cm3/molecule-sec at 25 C Atmospheric)
AUTOIGNITION

 

NFPA RATINGS Health: 2; Flammability: 0; Reactivity: 0

REFRACTIVE INDEX

 
FLASH POINT

 

STABILITY

Stable under ordinary conditions

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking

Material Safety Data Sheet

Google Scholar Search

Drug Information Portal (U.S. National Library of Medicine) - GLUTARALDEHYDE

http://oehha.ca.gov/
Glutaraldehyde is a chemical frequently used as a disinfectant and sterilizing agent against bacteria and viruses (2% solution), an embalming fluid and tissue fixative, a component of leather tanning solutions, and an intermediate in the production of certain sealants, resins, dyes, and electrical products (HSDB, 1996). For commercial purposes, solutions of 99%, 50%, and 20% are available. Glutaraldehyde is also an atmospheric reaction product of cyclohexene. The annual statewide industrial emissions from facilities reporting under the Air Toxics Hot Spots Act in California based on the most recent inventory were estimated to be 29,603 pounds of glutaraldehyde

http://www.cdc.gov/
Glutaraldehyde is a colorless, oily, liquid-chemical with a pungent odor. It is used for a number of applications such as the following:

  • A cold sterilant in the health care industry
  • A cross-linking and tanning agent
  • A biocide in metalworking fluids and in oil and gas pipelines
  • An antimicrobial in water-treatment systems
  • A slimicide in paper manufacturing
  • A preservative in cosmetics
  • A disinfectant in animal housing
  • A tissue fixative in histology and pathology labs
  • A hardening agent in the development of X-rays
  • In embalming solutions
  • In the preparation of grafts and bioprostheses
  • In various clinical applications

In the health care industry, glutaraldehyde is most often used to disinfect equipment that cannot be heat sterilized such as dialysis instruments, surgical instruments, suction bottles, bronchoscopes, endoscopes, and ear, nose, and throat instruments.

Local: Glutaraldehyde containing two aldehyde groups, is used as a disinfectant. It is used in sterilizing medical and dental equipment which cannot be heat sterilized. It is used as a fixative for biological tissues and for leather tanning. It is used as a chemical intermediate to produce other compounds.

GENERAL DESCRIPTION OF DISINFECTANT: Disinfectant is an agent applied to inanimate objects to destroy, neutralize, or inhibit the growth of disease-carrying microorganisms, (whereas antiseptics are applied primarily to living things). Heat and radiation are also disinfectants. Common ingredients of chemical disinfectant are:

  • Mercuric Chlorides
  • Formaldehyde
  • 8-Hydroxyquinoline
  • Copper Hydroxide
  • Cresol
  • Alcohols (Ethyl Alcohol; Isopropyl Alcohol)
  • Iodines / Iodophors
  • Chlorine releasing compounds
  • Gluteraldehyde
  • Phenolics
  • Quaternary Ammonium Compounds
SALES SPECIFICATION

50% SOLUTION, MEDICAL GRADE

APPEARANCE

Clear to yellowish liquid

CONTENT

50.% min

pH

3 - 5

BOILING POINT

ca 187 C

WATER

Balance

DENSITY

1.01 - 1.02

COLOR, APHA

50 max

METHANOL

1.0% max

50% SOLUTION, INDUSTRIAL GRADE

APPEARANCE

Clear to yellowish liquid

CONTENT

50.% min

pH

3 - 5

BOILING POINT

ca 187 C

MELTING POINT

-14 C

DENSITY

1.01 - 1.02

25% SOLUTION

APPEARANCE

Clear to yellowish liquid

CONTENT

25.0% min

WATER

Balance

COLOR, APHA

50 max

METHANOL

0.5% max

TRANSPORTATION
PACKING
200kgs in drum
HAZARD CLASS 6.1 (Packing Group II)
UN NO. 2927
SAFETY INFORMATION

GHS

 

SIGNAL WORD Danger

PICTOGRAMS

HAZARD STATEMENTS

H317:  May cause an allergic skin reaction
H335:  May cause respiratory irritation
H314:  Causes severe skin burns and eye damage
H334:  May cause allergy or asthma symptoms or breathing difficulties if inhaled
H301:  Toxic if swallowed
H331:  Toxic if inhaled
H400:  Very toxic to aquatic life

PRECAUTIONARY STATEMENTS

P280:  Wear protective gloves/protective clothing/eye protection/face protection
P270:  Do not eat, drink or smoke when using this product
P305 + P351 + P338:  IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing
P260:  Do not breathe dust/fume/gas/mist/vapors/spray
P308 + P313:  IF exposed or concerned: Get medical advice/attention
P273:  Avoid release to the environment

EC DIRECTIVES

HAZARD CODES

T ToxicN Dangerous for the environment

RISK PHRASES

23/25:  Toxic by inhalation and if swallowed.
34:  Causes burns.
42/43:  May cause sensitisation by inhalation and skin contact.
50:  Very toxic to aquatic organisms.

SAFETY PHRASES

26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
36/37/39:  Wear suitable protective clothing, gloves and eye/face protection.
45:  In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
61:  Avoid release to the environment. Refer to special instructions / safety data sheets.

PRICE INFORMATION