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| GUANYLTHIOUREA | ||
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PRODUCT IDENTIFICATION |
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| CAS NO. | 2114-02-5 |
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| EINECS NO. | 218-308-0 | |
| FORMULA | C2H6N4S | |
| MOL WT. | 118.16 | |
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H.S. CODE |
2930.90 | |
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TOXICITY |
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| SYNONYMS | Amidinothiourea; Aminoiminoethyl Thiourea; | |
| N-Amidinothiourea; 1-Amidinothiourea; 1-Amidino-2-thiourea; Thiodicyanodiamidine; Thiourea, (aminoiminomethyl)-; 1-guanyl-2-thiourea; Aminoiminoethyl thiourea; 2-Imino-4-tiobiuret; 1-Amidino-2-thioharnstoff (Dutch); 1-amidino-2-tiourea (Spanish); 1-amidino-2-thiourée (French); | ||
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CLASSIFICATION |
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PHYSICAL AND CHEMICAL PROPERTIES |
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| PHYSICAL STATE | white powder | |
| MELTING POINT | 171 - 173 C | |
| BOILING POINT | ||
| SPECIFIC GRAVITY | ||
| SOLUBILITY IN WATER | ||
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AUTOIGNITION |
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NFPA RATINGS |
Health: 1; Flammability: 0; Reactivity: 0 | |
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REFRACTIVE INDEX |
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| FLASH POINT | ||
| STABILITY |
Stable under ordinary conditions |
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GENERAL DESCRIPTION AND APPLICATIONS |
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| Thiourea (also called Thiocarbamide or Sulfourea) is the diamide of thiocarbonic acid that resembles urea but contains sulfur instead of oxygen. 'Thio' is a chemical prefix indicates the replacement of an oxygen in an acid radical by sulfur with a negative valence of 2; meaning 'Sulfur' derived from the Greek theion. In fct, thiourea occurs as the mixture of two tautomers: S=C(NH2)2 ( Thiourea) + HS=CNHNH2 (Isothiourea), accordingly, provides three functional groups (mino, imino, and thiol). Thiourea is a lustrous white crystalline compound; estimated melting point is 170-180 C; soluble in water and in polar organic solvents; insoluble in non-polar solvents. The exact melting point and boiling point are not available since rearrangement to ammonium thiocyanate (NH4SCN) occurs at about 135 C and decomposition occurs. It can be prepared by heating ammonium thiocyanate, or by the addition of hydrogen sulfide to cyanamide. The latter is the more common method. Thiourea is used directly in ore filtering, metal refinery and cleaning, isomerization catalyst (conversion of maleic to fumaric acid) and as an additive in fertilizers (to inhibit the nitrification process), drilling auxiliaries, light-sensitive photocopy paper and explosives. It is used as a fixing agent in photography, as a liquefying agent in animal hide glue, as an insecticide, as a textile-treating agent, and as an intermediate to produce other compounds. Thiourea and its derivatives are versatile intermediates for the synthesis of modified thermosetting resins, thiourea dioxide, dyes, flame retardants, vulcanization accelerators, plant protection agents, pesticides, amino resins, peptizing agents, fungicides, hair preparations, dry cleaning chemicals, corrosion inhibitors and thiazole drugs (e.g., antiseptic, thyrotherapeutic, narcotic, and tuberculostatic agents). Guanylthiourea is used as an intermediate of pharmaceuticals such as histamine H2-receptor antagonist [Famotidine : N'-(aminosulfonyl)-3-(((2-((diamino methylene) amino)-4-thiazolyl) methyl)thio) propanimidamide]. Dithiobiurea possesses a wide dipole moment and thus is involved in the forming wide metal chelated complexes as the radioactiv-compound which used in radiopharmaceutical imaging, inhibiting enzyme function, kidney function study and to treat toxic metal poisoning. It is used in co-crystals development used in the field of nonlinear optics to generate new coherent wavelengths. | ||
| SALES SPECIFICATION | ||
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APPEARANCE |
white powder | |
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ASSAY |
98.0% min | |
| MELTING POINT | 171 - 173 C | |
| TRANSPORTATION | ||
| PACKING |
25kgs
in fiber drum
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| HAZARD CLASS | Not regulated | |
| UN NO. | ||
| OTHER INFORMATION | ||
| Hazard Symbols: XN, Risk Phrases: 20/21/22, Safety Phrases: 23-24/25 | ||
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