ISONICOTINIC ACID

PRODUCT IDENTIFICATION

CAS NO. 55-22-1

ISONICOTINIC ACID

EINECS NO.

200-228-2

FORMULA C6H5NO2
MOL WT. 123.11

HS CODE

2933.39

TOXICITY

 
SYNONYMS Pyridine-4-carboxylic Acid; 4-Pyridinecarboxylic acid;
p-Pyridinecarboxylic Acid; Pyridine-carboxylique-4 (French); 4-Picolinic acid; Isonicotinsäure (German); ácido isonicotínico (Spanish); Acide isonicotinique (French);
SMILES

 

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE White to off-white crystalline solid
MELTING POINT

>310 C (sublimes)

BOILING POINT

 

SPECIFIC GRAVITY

 

SOLUBILITY IN WATER  
pH  
VAPOR DENSITY

 

NFPA RATINGS

Health: 1 Flammability: 0 Reactivity: 0 

AUTOIGNITION

 

REFRACTIVE INDEX

 

FLASH POINT

 

STABILITY Stable under normal conditions

APPLICATIONS

Isonicotinic acid, an isomer of nicotinic acid, is a six-membered ring structure compound composed of five carbon atoms and a nitrogen which replace one carbon-hydrogen unit in the benzene ring, plus a carboxyl side chain at 4-position (nicotinic acid has a carboxyl side chain at 3-position). Isonicotinic acid is chiefly used in antituberculosis drugs especially Isoniazid (isonicotinic acid hydrazide), the most effective one. Isonicotinic acid and its derivatives are used in manufacturing pharmaceuticals and agrochemicals. Niacin acts to reduce plasma cholesterol, as a vasodilator and to treat pellagra.  Niacin is used for the prophylaxis. Their derivatives are used for these effects.
SALES SPECIFICATION
APPEARANCE White to off-white crystalline solid

ASSAY

98.0% max
LOSS ON DRYING 0.5% max

HEAVY METALS

20ppm max

RESIDUE ON IGNITION

0.2% max

TRANSPORTATION
PACKING 25kgs in fiber drum
HAZARD CLASS  
UN NO.  
OTHER INFORMATION

Hazard Symbols: XI, Risk Phrases: 22-36/37/38, Safety Phrases: 26-36/37/39