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| ISOSORBIDE | ||
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PRODUCT IDENTIFICATION |
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| CAS NO. | 652-67-5 |
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| EINECS NO. | 211-492-3 | |
| FORMULA | C6H10O4 | |
| MOL WT. | 146.14 | |
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H.S. CODE |
2932.99 |
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TOXICITY |
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| SYNONYMS |
D-1,4:3,6-Dianhydroglucitol; Devicoran; |
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CLASSIFICATION |
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PHYSICAL AND CHEMICAL PROPERTIES |
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| PHYSICAL STATE |
Yellow to Greenish Solidified Mass | |
| MELTING POINT | 61 - 63 C | |
| BOILING POINT |
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| SPECIFIC GRAVITY |
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| SOLUBILITY IN WATER | ||
| pH | ||
| VAPOR DENSITY |
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AUTOIGNITION |
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NFPA RATINGS |
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REFRACTIVE INDEX |
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| FLASH POINT |
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| STABILITY | Stable under ordinary conditions. Hygroscopic. | |
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APPLICATIONS |
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| Isosorbide is a bicyclic ether derivative of glucitol. The nitric acid esters of isosorbide are used as osmotic diuretic to reduce intraocular pressure with effects on both arteries and veins and to treat coronary insufficiency and angina pectoris. The monoester is a white crystalline powder; melting point 140 C; freely soluble in water, alcohol and chloroform. The diester is a white crystalline powder; melting point 70 C; sparingly soluble in water; soluble in organic solvents; administered sublingually and orally. Eesters are explosive.. It should be diluted (25 - 40%) with lactose or mannitol for transportation. Chemical designation is 1,4:3,6-dianhydro-D-glucitol mono (di) nitrate. | ||
| SALES SPECIFICATION | ||
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APPEARANCE |
Yellow to Greenish Solidified Mass |
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PURITY (HPLC) |
98.0% min |
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SOLIDIFYING POINT |
59 C |
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| TRANSPORTATION | ||
| PACKING | 25kgs
in Drum | |
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| OTHER INFORMATION | ||
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