LUTEOLIN

PRODUCT IDENTIFICATION
CAS NO. 491-70-3

LUTEOLIN

EINECS NO.

207-741-0

FORMULA C15H10O6
MOL WT. 286.24

H.S. CODE

 2932.99.6100

TOXICITY

  
SYNONYMS 3',4',5,7-Tetrahydroxyflavone; 5,7,3',4'-Tetrahydroxyflavone; Luteolin;
2-(3,4-sihidroxifenil)-5,7-dihidroxi-4-benzopirona; 2-(3,4-dihydroxyphényl)- 5,7-dihydroxy-4-benzopyrone; Digitoflavone; Flacitran; C.I. 75590; C.I. Natural Yellow 2; Luteolol; Cyanidenon 1470; Flacitran;

SMILES

c12c(c(=O)cc(o1)c1cc(c(cc1)O)O)c(cc(c2)O)O

CLASSIFICATION

Natural Colorant, Flavone, Antioxidant

EXTRA NOTES

A 3'-hydroxyflavonoid which is thought to play an important role in the human body as an antioxidant, a free radical scavenger, an agent in the prevention of inflammation, a promoter of carbohydrate metabolism, and an immune system modulator.(ChEBI)

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE yellow crystalline powder
MELTING POINT

>320 C

BOILING POINT

 

SPECIFIC GRAVITY

 

SOLUBILITY IN WATER Sparingly soluble

SOLVENT SOLUBILITY

Soluble in alkalies

pH  
VAPOR DENSITY

 

REFRACTIVE INDEX

 

NFPA RATINGS

  

AUTOIGNITION

 

FLASH POINT

 

STABILITY Stable under normal conditions

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking - Luteolin

Google Scholar Search - Luteolin

Drug Information Portal (U.S. National Library of Medicine) - Luteolin

PubChem Compound Summary - Luteolin

KEGG (Kyoto Encyclopedia of Genes and Genomes) - Luteolin

http://www.ebi.ac.uk/ - Luteolin

http://www.ncbi.nlm.nih.gov/ - Luteolin

http://toxnet.nlm.nih.gov/
Hazardous Substances Data Bank - Luteolin

Local
Luteolin is a bioflavonel, considered to have bioactive effect on human health as antioxidant, radical scavenger, anti-inflammatory, carbohydrate metabolism promoter, immunity system modulater. It is considered to play a role in prevention of cancer. Members of luteolin molecules include:

Luteolin

CAS RN
Orobol 480-23-9
Chrysoeriol 491-71-4
Luteolin 491-70-3
Nepetin 520-11-6
Nepitrin 569-90-4
5,7,3',4'-Tetramethylluteolin 855-97-0

Homoorientin

 4261-42-1
Luteolin-7-glucoside 5373-11-5
6-Hydroxyluteolin 18003-33-3
Veronicastroside 25694-72-8
Luteolin glucoside 26811-41-6
Orientin 28608-75-5
Luteolin-7-glucuronide 29741-10-4
Chrysoeriol-7-O-(2''-O-mannopyranosyl)allopyranoside 137809-96-2
Luteolin-4'-O-(rhamnopyranosyl-1-2-glucopyranoside

n/a

Luteolin 7-O-glucoside 4''-sulfate

n/a

6-Hydroxyluteolin-7-O-glucoside

n/a

Luteolin-7-glucuronide

n/a

Luteolin 4'-O-glucoside

n/a

6-Hydroxyluteolin-7-O-(1''-rhamnoside)

n/a

Luteolin-7-galactoside

n/a

Luteolin-7-glucopyranosyl-1-6-glucoside

n/a
Luteolin 5-O-beta-rutinoside

n/a

Luteolin-7-glucopyranosyl-1-2-glucoside

n/a
Luteolin-7-O-beta-D-glucuronide

n/a

Luteolin 7-O-beta-D-apiofuranosyl-(1-2)-beta-D-glucopyranoside

n/a

Luteolin 3'-glucuronide

n/a

Luteolin-7-glucuronide methyl ester

n/a

Luteolin 8-C-rhamnoside-7-O-rhamnoside

n/a

Scolymoside

n/a

Luteolin-7-glucuronide ethyl ester

n/a
luteolin 7-O-(glucuronosyl-1-2-glucuronide)

n/a

Luteolin is classified as an ingredient of expectorant which ejects phlegm or other material from the throat or lungs by decreasing its viscosity or stimulating secretion of mucus by the respiratory tract mucosa.
SALES SPECIFICATION

APPEARANCE

 yellow crystalline powder

ASSAY

98.0% min

MELTING POINT

>320 C

GENERAL DESCRIPTION OF FLAVONOID
Flavonoid is any member of a class of widely distributed biological natural products containing aromatic heterocyclic skeleton of flavan (2-Phenylbenzopyran) but no nitrogen in plants. Generally, flavonoids are biological pigments providing colours from red to blue in flowers, fruit and leaves. Besides their coloring in plants, flavonoids have important roles in the growth and development of plants; protection against UV-B radiation; forming antifungal barriers; antimicrobial, insecticidal and oestrogenic activities; plant reproduction. Flavonoids also exhibit a wide range of biological properties including anti-microbial, insecticidal and oestrogenic activities. Flavonoids are usually classified into main 6 subgroups as below plus flavans, neoflavonoids, flavonols, aurons, catechins according to the structural patterns.
  • Flavonols (Hydroxy derivatives of flavone): Fisetin, Galangin, Kaempferide, Kaempferol, Morin, Myricetin, Myricitrin, Quercetin, Quercetrin, Rhamnetin, Robinin, Rutin, Spirenoside
  • Flavones (skeleton: 2-phenylchromen-4-one): Apigenin, Baicalein, Chrysin, Diosmetin, Diosmin, Flavone, Luteolin, Rpoifolin,Tangeretin, Techtochrysin, Rhamnazin, Nobiletin, Natsudaidain.
  • Isoflavones (skeleton: 3-phenylchromen-4-one): Daidzin, Genistein, Irilone, Luteone, Prunetin, Pratensein,
  • Flavonones (derivation by reduction of the 2(3) C=C bond): Eriodictyol, Hesperidin, Hesperetin, Likvirtin, Naringin; Naringenin; Pinocembrin
  • Flavanols (derivation by reduction of the keto group):(+)-Catechin, (+)-Gallocatechin, (-)-Epicatechin (EC), (-)-Epigallocatechin (EGC), (-)-Epicatechin 3-gallate (ECG), (-)-Epigallocatechin 3-gallate (EGCG), Theaflavin, Theaflavin 3-gallate, Theaflavin 3'-gallate, Theaflavin 3,3' digallate, Thearubigins
  • Anthocyanidins (aglycones of the glycoside anthocyanins): Apigeninidin, Cyanidin, Delphinidin, Diosmetinidin, Guibourtinidin, Fisetinidin, Luteolinidin, Malvidin, Pelargonidin, Peonidin, Robinetinidin, Tricetinidin, Capensinidin, Petunidin, Europinidin, Aurentinidin, Columnidin, 5-Desoxy-malvidin, 5-Desoxy-peonidin, Hirsutinidin, Rosinidin. 
TRANSPORTATION
PACKING
 
HAZARD CLASS  
UN NO. Not regulated
SAFETY INFORMATION

HAZARD OVERVIEW

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

GHS

 

SIGNAL WORD

Warning

PICTOGRAMS

HAZARD STATEMENTS

H315-H319-H335

P STATEMENTS

P261-P305 + P351 + P338

EC DIRECTIVES

 

HAZARD CODES

Xi

RISK PHRASES

36/37/38

SAFETY PHRASES

26-36

PRICE INFORMATION