N-CARBETHOXY-4-PIPERIDONE

PRODUCT IDENTIFICATION

CAS NO. 29976-53-2

n-CARBETHOXY-4-PIPERIDONE 

EINECS NO. 249-984-5
FORMULA C8H13NO3
MOL WT. 171.20

H.S. CODE

 

TOXICITY

 

SYNONYMS Ethyl 4-oxo-1-piperidinecarboxylate;
1-Ethoxycarbonyl-4-piperidone; N-Carbethoxy-4-piperidone; Ethyl 4-Oxopiperidine-1-carboxylate;
SMILES

 

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE Clear to yellow liquid
MELTING POINT  
BOILING POINT

147 - 151 C

SPECIFIC GRAVITY 1.13 - 1.14
SOLUBILITY IN WATER 500 (g/l at 20 C)
pH  
VAPOR DENSITY

 

AUTOIGNITION

 

NFPA RATINGS

Health: 1; Flammability: 2; Reactivity: 0

REFRACTIVE INDEX

 

FLASH POINT

 

STABILITY

Stable under ordinary conditions

APPLICATIONS

2-Piperidone, a keto-hydropyridine, is a 6-membered lactam structure compound (delta-valerolactam).  Lactam structure compounds including delta-valerolactam are good organic solvents soluble in water. Cyclic amides and analogues including N-alkyl lactams are biologically active nucleuses in pharmacologicals and flavorings. Lactams are widely used in artificial fibre industry. They are polymerizable and used as nylon precursors. They have excellent applications as solvents and as intermediates for organic synthesis. They are used in the aqueous carrier medium and amide penetrants in inks and water soluble paints. 4-Piperidone, a cyclic amide with ketone at para position, and its N-alkyl substituted derivatives are used in:
  • Alkene formation at the position of former carbonyl group. Alkene bonds are abundant in natural compounds
  • Sulfur compound removals
  • UV stabilizer products
  • Multicyclic hetero compounds and fused ring system compounds
  • Pharmaceutical synthesis including narcotic analgesics and digestive system drugs
  •  N-Carbethoxy-4-piperidone, a cyclic amide analogue containing ketone at 4 position and N-substituted carboxylic group branch, is used as an intermediate for biologically active pharmaceutical candidates. Example of finish product from N-carbethoxy-4-piperidone are heartburn treat drugs like cisapride.

    SALES SPECIFICATION

    APPEARANCE

    Clear to yellow liquid

    ASSAY

    98.0% min

    MOISTURE

    0.5% max
    TRANSPORTATION
    PACKING
    200kgs in drum
    HAZARD CLASS Not regulated
    UN NO.  
    OTHER INFORMATION
    Hazard Symbols: n/a, Risk Phrases: n/a, Safety Phrases: 24/25/28A/37/45