O6-METHYLGUANINE

PRODUCT IDENTIFICATION
CAS NO. 20535-83-5

O6-METHYLGUANINE
EINECS NO.  
FORMULA C6H7N5O
MOL WT. 165.15

H.S. CODE

  

TOXICITY

  
SYNONYMS 2-Amino-6-methoxypurine; 6-Methoxy-1H-Purin-2-amine;
O-Methylguanine; 6-Methoxyguanine;
SMILES

 

CLASSIFICATION

  

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE white to off-white crystalline powder
MELTING POINT > 300 C (Decomposes)
BOILING POINT  
SPECIFIC GRAVITY  
SOLUBILITY IN WATER Insoluble
pH  
VAPOR DENSITY

 

AUTOIGNITION

 

NFPA RATINGS

 Health: 1; Flammability: 1; Instability: 0

REFRACTIVE INDEX

 
FLASH POINT  
STABILITY

Stable under ordinary conditions

APPLICATIONS
Purine is a heterocyclic compound featured by a fused pyrimidine and imidazole rings composed of carbon and nitrogen atoms. The simplest one is purine itself and the two major purines are adenine(6-Aminopurine) and guanine(2-Amino-6-hydroxypurine) which are two bases components of nucleic acid and the nucleotides. Purine itself is not found in nature, but as substituted purines such as methyled, hydroxyl and amino substituted. In addition to adenine and guanine, a group of chemical compounds called purine base include hypoxanthine (6-oxypurine), xanthine (2,6-dioxypurine), uric acid (2,6,8-trioxypurine), and theobromine (3,7-dimethyl xanthine). Theophylline and caffeine are a member of methylated purine family. Purines are biologically important in In medicine and biological research.

O-6-Methylguanine is a methyl donor for 6-O-methylguanine-DNA methyl transferase (MGMT). It is used in various DNA replication mechanism studies.

SALES SPECIFICATION

APPEARANCE

 white to off-white crystalline powder

ASSAY

 99.0% min
MELTING POINT > 300 C
TRANSPORTATION
PACKING
 
HAZARD CLASS Not regulated
UN NO.  
OTHER INFORMATION
Hazard Symbols: XN , Risk Phrases: 22, Safety Phrases: 22-24/25