PROGESTERONE

PRODUCT IDENTIFICATION
CAS NO 57-83-0; 8012-32-6; 8023-13-0; 257630-50-5; 753497-20-0

MIFEPRISTONE
EINECS NO. 200-350-6
FORMULA C21H30O2
MOL WT. 314.46

H.S. CODE

  

TOXICITY

  
SYNONYMS Luteal Hormone; Delta4-pregnene-3,20-dione; 3,20-pregnene-4;
4-Pregnene-3,20-dione; Pregn-4-ene-3,20-dione; (S)-Pregn-4-en-3,20-dione;
SMILES

 

CLASSIFICATION

  

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE white to off-white crystalline powder
MELTING POINT 126 - 130 C
BOILING POINT Insoluble
SPECIFIC GRAVITY

 
SOLUBILITY IN WATER  
pH  
VAPOR DENSITY

 

REFRACTIVE INDEX

 

NFPA RATINGS

  

AUTOIGNITION

 
FLASH POINT

 
STABILITY Stable under ordinary conditions.

APPLICATIONS
Progesterone is a female sex hormone that plays an important physiological role to regularize and rebuild changes to the body caused by estrogen as well as in the luteal phase of the menstrual cycle. Its levels vary during the menstrual cycle. If fertilization occurs, it is produced during pregnancy by the placenta to prevent spontaneous abortion. If fertilization does not take place, the production of progesterone decreases and menstruation occurs. It is the hormone for the mammary glands of milk production. Progesterone is a steroid hormone consists chemically of four fused hydrocarbons containing the functional groups of ketone and aldehyde and two methyl branches. Progesterone is the precursor of all steroid hormones. It is an intermediate in the biosynthesis of androgens, estrogens, and the corticoids. Synthetic compounds with progesterone are used in the prevention of miscarriage, in the treatment of menstrual disorders. It is also used to develop a constituent of some oral contraceptives.

SALES SPECIFICATION

APPEARANCE

 white to off-white crystalline powder

IDENTIFICATION

Complies

ASSAY

97.0 - 102.0%

OPTICAL ROTATION

 +175° ~ +183°

LOSS ON DRYING

0.5% max
TRANSPORTATION
PACKING
 
HAZARD CLASS  
UN NO.  
OTHER INFORMATION
Hazard Symbols: XN, Risk Phrases: 40, Safety Phrases: 36/37-45
PROGESTERONE ANALOGUE
  • 19-Norprogesterone [CAS RN: 472-54-8]
  • Anhydrohydroxyprogesterone (Ethisterone) [CAS RN: 434-03-7]
  • Progesterone [CAS RN: 57-83-0]
  • 3alpha,5beta-Epimeric Pregnanolone (Eltanolone) [CAS RN: 128-20-1]
  • 16-Dehydroprogesterone [CAS RN: 1096-38-4]
  • 21-Hydroxyprogesterone (Reichstein substance Q) [CAS RN: 64-85-7]
  • 11alpha-Hydroxyprogesterone [CAS RN: 312-90-3, 80-75-1]
  • 11beta-Hydroxyprogesterone [CAS RN: 600-57-7]
  • 14alpha-Hydroxyprogesterone [CAS RN: 16031-66-6]
  • 17alpha-hydroxyprogesterone [CAS RN: 68-96-2]
  • 6beta-Hydroxyprogesterone
  • 16alpha-Hydroxyprogesterone [CAS RN: 438-07-3]
  • 17alpha-hydroxy-6alpha-methylprogesterone [CAS RN: 520-85-4]
  • 6alpha-Methyl-11beta-hydroxyprogesterone (Medrysone) [CAS RN: 2668-66-8]
  • 17,21-Dihydroxyprogesterone (Reichstein’s substance S) [CAS RN: 152-58-9]
  • 16alpha,17alpha-Dihydroxyprogesterone (Algestone) [CAS RN: 595-77-7]
  • 11,21-Dihydroxyprogesterone [CAS RN: 50-22-6]
  • 9-Fluoro-11beta,17-dihydroxyprogesterone (Flugestone) [CAS RN: 337-03-1]
  • 17alpha-Acetoxyprogesterone [CAS RN: 302-23-8]
  • 6-Dehydro-6-methyl-17alpha- acetoxyprogesterone (Megestrol acetate ) [CAS RN: 595-33-5]
  • 17alpha-Acetoxy-6-alpha-methylprogesterone [CAS RN: 71-58-9]
  • Progesterone 3-(O-carboxymethyl)oxime [CAS RN: 50909-89-2]
  • 6-Dehydro-17-hydroxy-6-methyl-16-methylene- progesterone acetate (Melengestrol acetate) [CAS RN: 2919-66-6]
  • 6-Chloro-delta 6-dehydro-17alpha- acetoxyprogesterone ( Chlormadinone acetate) [CAS RN: 302-22-7]
  • Haloprogesterone [CAS RN: 3538-57-6]
  • 17alpha-Hydroxyprogesterone caproate [CAS RN: 630-56-8]