PRODUCT IDENTIFICATION

57-67-0

C₇H₁₀N₄O₂S

214.24

H.S. CODE

TOXICITY

4-Amino-N-guanylbenzenesulfon Amide;

4-Amino-N-(diaminomethylene)benzenesulfon Amide; N1-Amidinosulfanilamide; N-Amidinosulfanilamide; Sulfaguanidine; Sulfanilyl guanadine;

CLASSIFICATION

PHYSICAL AND CHEMICAL PROPERTIES

AUTOIGNITION

NFPA RATINGS

REFRACTIVE INDEX

Stable under ordinary conditions

GENERAL DESCRIPTION AND APPLICATIONS

Sulfonamide is an organic sulfur compounds containing the radical -SO₂NH₂ (the amides of sulfonic acids). Its molecular structure is similar to p-Aminobenzoic acid (PABA) which is needed in bacteria organisms as a substrate of the enzyme dihydropteroate synthetase for the synthesis of tetrahydrofolic acid (THF). Sulfonamides, derived from chiefly sulfanilamide, are capable of interfering with the metabolic processes in bacteria that require PABA. They act as antimicrobial agents by inhibiting bacterial growth and activity and called sulfa drugs. They are used in the prevention and treatment of bacterial infections, diabetes mellitus, edema, hypertension, and gout. Sulfa drug includes;

• Topical sulfonamides: sulfacetamide; silver sulfadiazine; mafenide; 
• Rapidly absorbed and eliminated sulfonamides: sulfisoxazole diolamine; sulfadiazine; sulfamethoxazole;
• Hydrophylic sulfonamides: phtalylsulfacetamide; phtalylsulfathiazole; sulfasalazine; sulfaguanidine;
• Long lasting sulfonamides: sulfadoxine; 
• Others: sulfamazole; sulfamazone; sulfametopirazine; sulfametoxypiridazine; sulfametrol; succinylsulfathiazole; 

Sulfaguanidine is used in the treatment of gastrointestinal infections particularly bacillary dysentery.

APPEARANCE

IDENTITY

pass

CONTENT

98.0% min

189 - 192 C

HEAVY METALS

20ppm max

CHLORIDE

100ppm mac

SULFATE

200ppm max

WATER

6.0 - 8.0%

0.1% max