The taxanes (or called taxoids) are a class of diterpenoid cyclodecanes that were first derived from the plants of the genus Taxus tree. The taxan molecule consists of a tetracyclic motif (four ring members fused ; cyclohexane, cyclooctane, cyclohexane and oxacyclobutane) called baccatin III and amide moiety. 10-Deacetylbaccatin III is found in larger quantities than the most active paclitaxel in the plant. This compound is used as a starting material to prepare semi-synthetic paclitaxel. Taxanes have been used as antineoplastic agents with varying degrees of antitumor activity. Taxane drug inhibits cell growth or properly dividing which lead to cell death by promoting and stabilizing the polymerization of microtubules. The members include paclitaxel (taxol), docetaxel (taxotere), and related compounds. Taxine is the mixture of taxoids. Taxanes are also known to be a radiosensitizing.