beta-SITOSTEROL

PRODUCT IDENTIFICATION

CAS NO. 83-46-5

beta-SITOSTEROL

EINECS NO.

201-480-6

FORMULA C29H50O
MOL WT. 414.71

H.S. CODE

2906.13.5000

TOXICITY

 
SYNONYMS Stigmast-5-en-3beta-ol;
22,23-Dihydro-Stigmasterol; beta-Sitosterin; Angelicin; Cinchol; Cupreol; Rhamnol; (3beta)-Stigmast-5-en-3-ol; alpha-Dihydrofucosterol; Quebrachol; 24alpha-Ethylcholesterol; 5-Cholesten-24beta-ethyl-3beta-ol; Stigmast-5-en-3-ol;
SMILES

[C@@]12([C@H]([C@H]3[C@@H]([C@@]4(C(=CC3)C[C@H] (CC4)O)C)C C2) CC[C@@H]1[C@@H](CC[C@@H] ([C@H](C)C)CC) C)C

CLASSIFICATION

Phytosterol

EXTRA NOTES

β-Sitosterol is one of several phytosterols (plant sterols) with chemical structures similar to that of cholesterol. (wikipedia)
Other RN: 8003-23-4, 15764-35-9 76772-70-8 182512-23-8

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE white solid
MELTING POINT 130 - 145 C
BOILING POINT

 

SPECIFIC GRAVITY

 

SOLUBILITY IN WATER Practically soluble (soluble in ethanol)
pH  
VAPOR DENSITY

 

REFRACTIVE INDEX

 

NFPA RATINGS

Health: 1; Flammability: 0; Reactivity: 0

AUTOIGNITION

 

FLASH POINT

 

STABILITY Stable under normal conditions

EXTERNAL LINKS & GENERAL DESCRIPTION

USA.gov - beta-Sitosterol

Wikipedia Linking - beta-Sitosterol

Google Scholar Search - beta-Sitosterol

U.S. National Library of Medicine - beta-Sitosterol

PubChem Compound Summary - beta-Sitosterol

KEGG (Kyoto Encyclopedia of Genes and Genomes) -  beta-Sitosterol

http://www.ebi.ac.uk/chebi/ -  beta-Sitosterol

http://www.ncbi.nlm.nih.gov/ -  beta-Sitosterol

EPA - Substance Registry Services - beta-Sitosterol

Local:
Phytosterol: various sterols naturally obtained from plants. It is chemically similar to cholesterol which is obtained from animals. Sterol consists of three fused cyclohexane rings with hydrophenanthrene ring arrangement; the side chains vary sterols (more than 40 phytosterols are known). Beta-sitosterol is the most abundant phytosterol and others include campesterol, stigmasterol, ergosterol, brassicasterol, delta-7-stigmasterol and delta-7-avenasterol. They are waxy, clear solids soluble in most organic solvents but insoluble in water, and contain one alcohol functional group. Sitosterols are considered to play roles in lowering cholesterol in body (anticholesterolemic agent). stigmasterol is an unsaturated plant sterol occurring in plant fats like such as calabar bean, soybean oil, rape seed and cocoa butter. It is used as a starting material in the manufacture of synthetic progesterone, a female sex hormone that plays an important physiological role to regularize and rebuild  changes to the body caused by estrogen as well as in the luteal phase of the menstrual cycle. Its levels vary during the menstrual cycle.  In addition, progesterone is used as an intermediate in the biosynthesis of androgens, estrogens, and the corticoids. Synthetic compounds with progesterone are used in the prevention of miscarriage, in the treatment of menstrual disorders. Ergosterol, also called provitamin D2, is an unsaponifiable lipids; found in ergot, yeast, and other fungi; a white crystalline compound insoluble in water and soluble in organic solvents. It is converted to ergocalciferol (vitamin D2) upon irradiation by ultraviolet light or electronic bombardment.  vitamin D is either of two fat-soluble sterol-like compounds with antirachitic activity, or both collectively: ergocalciferol (vitamin D2) and activated cholecalciferol (vitamin D3). Ergocalciferol is formed from the irradiation of ergosterol found in dietary supplements such as fish liver oils, egg yolks, and fortified dairy products. However, cholecalciferol is normally synthesized in the skin, where ultraviolet light activates the compound 7-dehydrocholesterol. Vitamins D2 and D3 are about equal in activity in all mammals. Deficiency of vitamin D can result in rickets in children and osteomalacia in adults, while ingestion of excess levels can lead to hypercalcemia, mobilization of calcium from bone, and renal dysfunction.

SALES SPECIFICATION

APPEARANCE

white crystals

STEROL COMPOSITION

Phytosterols: 95% min

beta Sitosterol: 40% min

Stigmasterol: 15 - 30%

Campesterol :15 - 30%

Brassicasterol: 5.0%min

beta-SITOSTEROL

40.0% min

HEAVY METALS

20ppm max

ARSENIC

1ppm max

LEAD

none

ASH

1.0% max

MICROBIOLOGICAL TESTS Total plate count: 1000CFU/g mac
Yeast and mold: 100CFU/g
Salmonella: negative
E.Coli: negative
Staphylococcus: negative
P.Aeruginosa: negative

MELTING POINT

130 - 145 C
TRANSPORTATION
PACKING
 
HAZARD CLASS  
UN NO.  
OTHER INFORMATION
Hazard Symbols: , Risk Phrases: , Safety Phrases: 24/25-28A-37-45
ANTILIPEMIC AGENTS



PRICE INFORMATION