N-CHLOROSUCCINIMIDE

PRODUCT IDENTIFICATION
CAS NO. 128-09-6

n-CHLOROSUCCINIMIDE

EINECS NO. 204-878-8
FORMULA C4H4ClNO2
MOL WT. 133.53

H.S. CODE

TOXICITY
SYNONYMS 1-Chloro-2,5-pyrrolidinedione; Succinochlorimide;
NCS; Chlorosuccinimide; 1-chloro-Pyrrolidinedione; N-氯代琥珀酰亚胺; Succinic N-Chloroimide
SMILES

 

CLASSIFICATION

  

PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE white to off-white crystalline powder
MELTING POINT 144 - 148 C
BOILING POINT

 

SPECIFIC GRAVITY

1.65

SOLUBILITY IN WATER Slightly soluble
pH  
VAPOR DENSITY

 

AUTOIGNITION

 

NFPA RATINGS

  

REFRACTIVE INDEX

 

FLASH POINT

 

STABILITY Stable under ordinary conditions. light and moisture sensitive

APPLICATIONS

N-Chlorosuccinimide is used as an intermediate or a chlorinating agent in the synthesis of pharmaceuticals especially for tetracycline antibiotics (chlortetracycline, oxytetracycline, tetracycline, demeclocycline, methacycline, doxycycline and minocycline. ). Carbon-carbon double bonds add chlorine and bromine rapidly in liquid phase. Halogen substitution reaction of alkenes should be carried out in the gas phase with halogenating reagents such as N-bromosuccinimide and N-Chlorosuccinimide. Allylic halogenations are carried in the liquid phase.
SALES SPECIFICATION

APPEARANCE

 white to off-white crystalline powder

CONTENT

98.0% min
CHLORIDE CONTENT

25.0% min
TRANSPORTATION
PACKING

20kgs in fiber drum

HAZARD CLASS 8 9Packing Group: III)
UN NO. 1759
OTHER INFORMATION
Hazard Symbols: XN, Risk Phrases: 22/36/37/38, Safety Phrases: 26/37/39