|
ACACETIN |
| Synonyms. Acacetin; 5,7-Dihydroxy-4'-methoxyflavone; Apigenin 4'-methyl ether; Apisenin 4'-methyl ether; Buddleoflavonol; Linarigenin; 5,7-Dihydroxy-2-(4-methoxyphenyl)-4-benzopyrone; 4'-Methoxyapigenin; 5,7-Dioxy-4'-methoxyflavone; Acacetine; Akatsetin; Apigenin 4'-dimethyl ether; 5,7-Dihydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one; |
|
|
| PRODUCT IDENTIFICATION | |
|
CAS RN |
480-44-4 |
|
EINECS RN |
207-552-3 |
|
FORMULA |
C16H12O5 |
|
MOLE WEIGHT |
284.26 |
|
H.S CODE |
2932.99.6100 |
|
SMILES |
c12c(oc(c3ccc(OC)cc3)cc1=O)cc(O)cc2O |
|
CLASSIFICATION |
Flavone, Antioxidant, Cytoprotectant |
|
EXTRA NOTES |
Flavonoid with anti-peroxidative and anti-inflammatory properties. Used in traditional Chinese medicine. It has been recognized as an antiproliferative agent on cancer cell lines by inducing apoptosis and blocking cell cycle progression in the G1 phase. (SigmaAldrich) |
|
|
| PHYSICAL AND CHEMICAL PROPERTIES | |
|
PHYSICAL STATE. |
white crystalline powder |
|
MELTING POINT |
260 ~ 265 C |
|
BOILING POINT |
|
|
DENSITY |
|
|
SOLUBILITY IN WATER |
|
| SOLVENT SOLUBILITY | Soluble in hot alcohol, alkalies. Practically insoluble in ether. |
|
VAPOR DENSITY |
|
|
log P(octanol-water) |
3.40 |
|
VAPOR PRESSURE |
|
|
AUTOIGNITION TEMP |
|
| pK |
|
|
REFRACTIVE INDEX |
|
|
FLASH POINT |
|
|
|
| STABILITY AND REACTIVITY | |
| STABILITY | Stable under normal conditions. |
|
INCOMPATIBLE MATERIALS |
Strong oxidizing agents. |
| POLYMERIZATION |
Has not been reported |
|
NFPA RATINGS |
Health: 1, Flammability: 0, Reactivity: 0 |
|
|
| EXTERNAL LINKS & GENERAL DESCRIPTION |
|
Wikipedia Linking - Acacetin Google Scholar Search - Acacetin Drug Information Portal (U.S. National Library of Medicine) - Acacetin PubChem Compound Summary - Acacetin KEGG (Kyoto Encyclopedia of Genes and Genomes) - Acacetin http://www.ebi.ac.uk/ - Acacetin http://www.ncbi.nlm.nih.gov/ - Acacetin |
|
|
| SALES SPECIFICATION | |
|
APPEARANCE |
white crystalline powder |
|
ASSAY |
98.0% min |
|
MELTING POINT |
260 ~ 265 C |
|
HEAVY METALS |
20ppm max |
|
|
| TRANSPORT & REGULATORY INFORMATION | |
|
UN NO. |
Not regulated |
| HAZARD CLASS |
|
| PACKING GROUP | |
|
|
| SAFETY INFORMATION | |
|
HAZARD OVERVIEW |
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. |
|
GHS |
|
|
SIGNAL WORD |
Warning |
|
PICTOGRAMS |
|
|
HAZARD STATEMENTS |
H315-H319-P335 |
|
P STATEMENTS |
P261-P305 + P351 + P338 |
| EC DIRECTIVES |
|
| HAZARD CODES |
|
|
RISK PHRASES |
36/37/38 |
|
SAFETY PHRASES |
26-36 |
Xi|
|
| PACKING |
|
Preserve in light-resistant and well-closed containers |