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ALARELIN |
| Synonyms. Alarelin; Alarelin Acetate; ala(6)-gly(10)-ethylamide-LHRH; 10-Des-gly,6-(D-ala)-LHRH ethylamide acetate salt; 6-D-Ala-10-D-gly-LHRH-ethylamide Ala(6)-gly(10)-gnrh; LHRH-A; Des-Gly(sup 10),(D-Ala(sup 6))-LHRH-ethylamide; 6-D-Alanine-9-(N-ethyl-L-prolinamide)-10-deglycinamide- luteinizing hormone-releasing factor diacetate; [Des-Gly10, D-Ala6]-LH-RH ethylamide acetate; Glp-His-Trp-Ser-Tyr-Ala-Leu-Arg-Pro-NHEt; |
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| PRODUCT IDENTIFICATION | |
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CAS RN |
79561-22-1 |
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EINECS RN |
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FORMULA |
C56H78N16O12·xC2H4O2·yH2O |
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MOLE WEIGHT |
1167.32 (anhydrous free base basis) |
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H.S CODE |
2933.99.7900 |
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SMILES |
c1cc2c(cc1)c(C[C@H](NC([C@H](Cc1[nH]cnc1)NC(=O)[C@ @H]1NC (CC1) =O)=O)C(N[C@H] (C(N[C@@H](Cc1ccc(cc1)O) C(=O)N[C@@H] (C(N[C @H](C(N[C@H](C(N1CCC[C@H]1C (=O) NCC)=O)CCCNC(N)=N)=O) CC(C) C)=O)C)=O)CO)=O)c[nH]2. C(C)(O)=O.C(C)(O)=O |
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CLASSIFICATION |
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EXTRA NOTES |
A growth hormone agonistic analog |
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| PHYSICAL AND CHEMICAL PROPERTIES | |
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PHYSICAL STATE. |
white powder |
MELTING POINT |
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BOILING POINT |
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DENSITY |
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SOLUBILITY IN WATER |
Miscible |
| SOLVENT SOLUBILITY | |
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VAPOR DENSITY |
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log P(octanol-water) |
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VAPOR PRESSURE |
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AUTOIGNITION TEMP |
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| pKa |
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REFRACTIVE INDEX |
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FLASH POINT |
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| STABILITY AND REACTIVITY | |
| STABILITY | Stable under normal conditions. |
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INCOMPATIBLE MATERIALS |
Strong oxidizing agents |
| POLYMERIZATION |
Has not been reported |
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NFPA RATINGS |
Health: 0, Flammability:0, Reactivity: 0 |
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| EXTERNAL LINKS & GENERAL DESCRIPTION |
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Wikipedia Linking - Alarelin Google Scholar Search - Alarelin Drug Information Portal (U.S. National Library of Medicine) - Alarelin PubChem Compound Summary - Alarelin Drug Bank - Alarelin KEGG (Kyoto Encyclopedia of Genes and Genomes) - Alarelin http://www.ebi.ac.uk/ - Alarelin http://www.ncbi.nlm.nih.gov/ - Alarelin http://toxnet.nlm.nih.gov/
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| SALES SPECIFICATION |
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APPEARANCE |
white powder |
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ASSAY |
95.0~105.0% (on Anhydrous, Acetic Acid free basis) |
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OPTICAL ROTATION |
-47.0° ~ -57.0° (c=1,1% HAc) |
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WATER |
8.0% max (Karl Fischer) |
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ACETATE CONTENT |
15.0% max (HPLC) |
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AMINO ACID COMPOSITION |
±10% theoretical |
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INDIVIDUAL IMPURITY |
1.0% max (HPLC) |
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PEPTIDE CONTENT |
80% min (by %N) |
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| TRANSPORT & REGULATORY INFORMATION | |
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UN NO. |
Not regulated |
| HAZARD CLASS |
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| PACKING GROUP | |
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| SAFETY INFORMATION | |
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HAZARD OVERVIEW |
May damage fertility or the unborn child. Reproductive hazard |
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GHS |
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SIGNAL WORD |
Danger |
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PICTOGRAMS |
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HAZARD STATEMENTS |
H360 |
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P STATEMENTS |
P201-P308 + P313 |
| EC DIRECTIVES |
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| HAZARD CODES |
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RISK PHRASES |
60 |
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SAFETY PHRASES |
45-53 |
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| PACKING |
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| PRICE INFORMATION |
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