ALOGLIPTIN

Synonyms. Alogliptin; 2-((6-((3R)-3-amino-1-piperidinyl)-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)- pyrimidinyl)methyl)benzonitrile; 6-((3R)-3-aminopiperidin-1-yl)-1-(2-cyanobenzyl)-3-methylpyrimidin- 2,4(1H,3H)-dione

ALOGLIPTIN

 

PRODUCT IDENTIFICATION

CAS RN

850649-61-5

EINECS RN

 

FORMULA

C18H21N5O2

MOLE WEIGHT

339.39

H.S CODE

2933.99.7500

SMILES

n1(c(=O)cc(n(c1=O)Cc1c(cccc1)C#N)N1C[C@@H](CCC1)N)C

CLASSIFICATION

Dipeptidyl-Peptidase IV Inhibitor, Hypoglycemic agent, Protease Inhibitor

EXTRA NOTES

Treatment of type 2 diabetes

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE.

white powder

MELTING POINT

 

BOILING POINT

519 ~ 520 C

DENSITY

1.34

SOLUBILITY IN WATER

 

SOLVENT SOLUBILITY  

VAPOR DENSITY

 

log P(octanol-water)

 

VAPOR PRESSURE

 

AUTOIGNITION TEMP

 
pKa

 

REFRACTIVE INDEX

 

FLASH POINT

267 C

 

STABILITY AND REACTIVITY
STABILITY Stable under normal conditions.

INCOMPATIBLE MATERIALS

Strong oxidizing agents

POLYMERIZATION

Has not been reported

NFPA RATINGS

Health: 0, Flammability:0, Reactivity: 0

 

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking - Alogliptin

Google Scholar Search - Alogliptin

Drug Information Portal (U.S. National Library of Medicine) - Alogliptin

PubChem Compound Summary - Alogliptin

Drug Bank -  Alogliptin

KEGG (Kyoto Encyclopedia of Genes and Genomes) - Alogliptin

http://www.ebi.ac.uk/ - Alogliptin

http://www.ncbi.nlm.nih.gov/ - Alogliptin

http://toxnet.nlm.nih.gov/
Hazardous Substances Data Bank -  Alogliptin

Dipeptidyl peptidase-4 inhibitors

Product

CAS RN.

Alogliptin

850649-61-5

Alogliptin benzoate

850649-62-6

Gemigliptin

911637-19-9

Linagliptin

668270-12-0

Saxagliptin

361442-04-8

Saxagliptin hydrate

945667-22-1

Sitagliptin

486460-32-6

Vildagliptin

274901-16-5

 

SALES SPECIFICATION

APPEARANCE

off-white to yellow powder

ASSAY

98.0% min

LOSS ON DRYING

5.0% max

HEAVY METALS

10ppm max

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

Not regulated

HAZARD CLASS

 
PACKING GROUP  

 

SAFETY INFORMATION

HAZARD OVERVIEW

Not known

HAZARD CODES

 

RISK PHRASES

 

SAFETY PHRASES

 

 

PACKING

 

 

PRICE INFORMATION