AMENTOFLAVONE

Synonyms. Amentoflavone; Didemethyl-ginkgetin; 3',8''-Biapigenin; 8-(5-(5,7-dihydroxy-4-oxo-1- benzopyran- 2-yl)-2-hydroxyphenyl)-5,7- dihydroxy-2-(4-hydroxyphenyl)- 1-benzopyran-4-one; 8-(5-(5,7- dihydroxy-4-oxochromen-2-yl)-2-hydroxyphenyl)-5,7- dihydroxy-2-(4-hydroxyphenyl) chromen- 4-one; 8-(5-(5,7-bis(oxidanyl)-4-oxidanylidene-chromen-2-yl)-2- oxidanyl-phenyl)-2- (4-hydroxyphenyl)-5,7- bis(oxidanyl)chromen-4-one; 3',8-Bi[4',5,7-trihydroxyflavone]; 4',4''',5,5'',7,7''-Hexahydroxy-3''', 8-biflavone; 4',5,7-Trihydroxyflavone(3'->8)-4',5,7-trihydroxyflavone;

AMENTOFLAVONE

Click for original image

 

PRODUCT IDENTIFICATION

CAS RN

1617-53-4

EINECS RN

 

FORMULA

C30H18O10

MOLE WEIGHT

538.46

H.S CODE

2932.99.6100

SMILES

c1(cc(c2c(o1)c(c(cc2O)O)c1c(ccc(c1)c1cc(c2c(o1)cc (cc2O)O)=O)O)= O) c1 ccc(cc1)O

CLASSIFICATION

Flavone, Anti-angiogenic, Anti-inflammatory

EXTRA NOTES

Amentoflavone is found in fruits. Amentoflavoneis obtained from Viburnum prunifolium (black haw) Amentoflavone has been shown toexhibit anti-angiogenic and anti-inflammatory functions (PMID 21471210, 9875467). Amentoflavone belongs to the family of Biflavonoids and Polyflavonoids. These are organic compounds containing at least two flavan derivatives. (HMDB)

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE.

light yellow power

MELTING POINT

> 300 C

BOILING POINT

 

DENSITY

 

SOLUBILITY IN WATER

Practically insoluble

SOLVENT SOLUBILITY

 

VAPOR DENSITY

 

log P(octanol-water)

 

VAPOR PRESSURE

 

AUTOIGNITION TEMP

 
pH

 

REFRACTIVE INDEX

 

FLASH POINT

 

 

STABILITY AND REACTIVITY
STABILITY Stable under normal conditions.

INCOMPATIBLE MATERIALS

Strong oxidizing agents

POLYMERIZATION

Has not been reported

NFPA RATINGS

Health: 0, Flammability:0, Reactivity: 0

 

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking - Amentoflavone

Google Scholar Search - Amentoflavone

Drug Information Portal (U.S. National Library of Medicine) - Amentoflavone

PubChem Compound Summary - Amentoflavone

KEGG (Kyoto Encyclopedia of Genes and Genomes) - Amentoflavone

http://www.ebi.ac.uk/ - Amentoflavone

http://www.ncbi.nlm.nih.gov/ - Amentoflavone

 

SALES SPECIFICATION

APPEARANCE

light yellow power

CONTENT

98.0% min

LOSS ON DRYING

1.0% max

HEAVY METALS

20ppm max

MELTING POINT

> 300 C

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

Not regulated

HAZARD CLASS

 
PACKING GROUP  

 

SAFETY INFORMATION

HAZARD OVERVIEW

May be harmful if inhaled. May cause respiratory tract irritation. May be harmful if absorbed through skin. May cause skin irritation. May cause eye irritation. May be harmful if swallowed. OSHA Hazards: Not known

EC DIRECTIVES

 

HAZARD CODES

 

RISK PHRASES

 

SAFETY PHRASES

22-24/25

 

PACKING

Preserve in light-resistant and well-closed containers