AUCUBIN

Synonyms. Aucubin; 1,4a,5,7a-Tetrahydro-5-hydroxy-7-hydroxymethylcyclopenta(c)pyran-1-yl-beta-D- glucopyranoside; (1S-(1alpha,4aalpha,5alpha,7aalpha))-1,4a,5,7a-Tetrahydro-5-hydroxy-7- (hydroxy methyl) cyclopenta(c)pyran -1-yl-beta-D-glucopyranoside; 2-Nitroimidazole azomycin; Rhinanthin;

AUCUBIN

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PRODUCT IDENTIFICATION

CAS RN

479-98-1

EINECS RN

207-540-8

FORMULA

 C15H22O9

MOLE WEIGHT

346.33

H.S CODE

 2932.99.6100

SMILES

 O[C@@H]1C=C([C@H]2[C@@H](OC=C[C@@H]12)O[C@@H]1O[C@H](CO) [C@@H] (O) [C@@H](O)[C@H]1O)CO

CLASSIFICATION

Iridoid

EXTRA NOTES

 Aucubin is a monoterpenoid based compound. Aucubin, like all iridoids, has a cyclopentan-[C]-pyran skeleton. Iridoids can consist of ten, nine, or rarely eight carbons in which C11 is more frequently missing than C10

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE.

white to off-white crystalline powder

MELTING POINT

181 C

BOILING POINT

 

DENSITY

 

SOLUBILITY IN WATER

Soluble

SOLVENT SOLUBILITY Soluble in methanol, practically insoluble in chloroform, ether, petroleum ether

VAPOR DENSITY

 

log P(octanol-water)

 -3.49

VAPOR PRESSURE

  

AUTOIGNITION TEMP

  
pH

 

REFRACTIVE INDEX

 

FLASH POINT

 

 
STABILITY AND REACTIVITY
STABILITY Stable under normal conditions.

INCOMPATIBLE MATERIALS

Strong oxidizing agents.

POLYMERIZATION

Has not been reported

NFPA RATINGS

Health: 0, Flammability: 0, Reactivity: 0

 

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking - Aucubin

Google Scholar Search - Aucubin

Drug Information Portal (U.S. National Library of Medicine) - Aucubin

PubChem Compound Summary - Aucubin

Drug Bank -  Aucubin

KEGG (Kyoto Encyclopedia of Genes and Genomes) - Aucubin

http://www.ebi.ac.uk/ - Aucubin

http://www.ncbi.nlm.nih.gov/ - Aucubin

http://www.biochemj.org/
Some of the many types of glycosides which have been described have been thought to be specific products of narrow taxonomic groups of plants. However, more and more of them are proving to occur widely in the plant kingdom. The work described in this paper shows that aucubin, asperuloside and related glycosides, which are probably derived from substituted furan aglycones, constitute one such widely occurring type. Aucubin was first isolated by Bourquelot & H6rissey (1905) from the leaves of Aucuba japonica (family Cornaceae). It is a monohydrate of a monoglucoside of an unstable aglucone, which these workers were unable to isolate or identify....

 

SALES SPECIFICATION

APPEARANCE

white to off-white crystalline powder

ASSAY

98.0% min

MELTING POINT

180 ~ 183 C
SPECIFIC ROTATION

-160.0° ~ -165.0° (c =1.6 in H2O)

HEAVY METALS

10ppm max

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

Not regulated

HAZARD CLASS

  
PACKING GROUP  

 

SAFETY INFORMATION

HAZARD OVERVIEW

OSHA Hazards:Not known. May be harmful if inhaled. May cause respiratory tract irritation. May be harmful if absorbed through skin. May cause skin irritation. May cause eye irritation. May be harmful if swallowed.

EC DIRECTIVES

 

HAZARD CODES

 

RISK PHRASES

22

SAFETY PHRASES

 22-45

 

PACKING