COELENTERAZINE

Synonyms. Coelenterazine; Oplophorus luciferin; 2-(p-Hydroxybenzyl)-6-(p-hydroxyphenyl)-8-benzyl-imidazo[1,2-a]pyrazin-3-(7H)-one; 3,2-Dihydro-2-(p-hydroxybenzyl)-6-(p-hydroxyphenyl)-8-benzylimidazolo[1,2-a]pyrazin-3-one; CLZN; 2-(4-Hydroxybenzyl)-6-(4-hydroxyphenyl)-8-benzyl-3,7-dihydroimidazo(1,2-a)pyrazin-3-one;

COELENTERAZINE

Click for original image

 

PRODUCT IDENTIFICATION

CAS RN

55779-48-1

EINECS RN

 

FORMULA

 C26H21N3O3

MOLE WEIGHT

423.46

H.S CODE

 2934.90.9000

SMILES

 n12c(nc(c1=O)Cc1ccc(cc1)O)c([nH]c(c2)c1ccc(O)cc1)Cc1ccccc1

CLASSIFICATION

Luminescent Agent

EXTRA NOTES

Luminophore of the aequorin complex which is oxidized by oxygen to illuminate at 465 nm when Ca2+ binds to the complex; used to measure Ca2+ concentration in cells with high sensitivity and large dynamic range (sigmaaldrich)

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE.

yellowish to brown crystalline powder

MELTING POINT

175 ~ 179 C

BOILING POINT

 

DENSITY

 

SOLUBILITY IN WATER

 

SOLVENT SOLUBILITY

 

VAPOR DENSITY

 

log P(octanol-water)

  

VAPOR PRESSURE

  

AUTOIGNITION TEMP

  
pH

 

REFRACTIVE INDEX

 

FLASH POINT

 

 

STABILITY AND REACTIVITY
STABILITY Stable under normal conditions. Light sensitive.

INCOMPATIBLE MATERIALS

Strong oxidizing agents.

POLYMERIZATION

Has not been reported

NFPA RATINGS

Health: 0, Flammability: 0, Reactivity: 0

 

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking - Coelenterazine

Google Scholar Search - Coelenterazine

Drug Information Portal (U.S. National Library of Medicine) - Coelenterazine

PubChem Compound Summary - Coelenterazine

KEGG (Kyoto Encyclopedia of Genes and Genomes) - Coelenterazine

Chemical Entities of Biological Interest (ChEBI) - Coelenterazine

http://www.ncbi.nlm.nih.gov/ - Coelenterazine

http://www.lifesci.ucsb.edu/
Major Luciferin Types - Although there are hundreds of types of luminous animals in the sea, there are surprisingly few basic luciferins (light emitters) which have been found in across many species. In some cases this conservation can be explained by animals acquiring luciferin through the food chain, but in other cases organisms have been shown to have the ability to synthesize the same chemical on their own.

 

SALES SPECIFICATION

APPEARANCE

yellowish to brown crystalline powder

PURITY

95.0% min (TLC)

MELTING POINT

175 ~ 179 C

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

 

HAZARD CLASS

  
PACKING GROUP  

 

SAFETY INFORMATION

HAZARD OVERVIEW

OSHA Hazards:No known hazards. May cause long lasting harmful effects to aquatic life. Eyes: Causes eye irritation. Skin: May be harmful if absorbed through skin. Causes skin irritation. Inhalation: May be harmful if inhaled. Causes respiratory tract irritation. Ingestion: May be harmful if swallowed.

GHS

  

SIGNAL WORD

Warning

PICTOGRAMS

HAZARD STATEMENTS

H413

P STATEMENTS

 

EC DIRECTIVES

 

HAZARD CODES

RISK PHRASES

36/37/38

SAFETY PHRASES

 24/25-26-28-36/37/39

 

PACKING

Preserve in light-resistant and well-closed containers

 

PRICE INFORMATION