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DITHIOERYTHRITOL |
| Synonyms. Dithioerythritol; 1,4-Dithioerythritol; (R',S')-1,4-Dimercaptobutane-2,3-diol; erythro-1,4-Dimercapto-2,3-butanediol; erythro-2,3-Dihydroxy-1,4-butanedithiol; Cleland's reagent; DTE; (2R,3S)-1,4-bis(sulfanyl)butane-2,3-diol; DTU; |
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| PRODUCT IDENTIFICATION | |
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CAS RN |
6892-68-8 |
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EINECS RN |
229-998-8 |
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FORMULA |
HSCH2CH(OH)CH(OH)CH2SH |
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MOLE WEIGHT |
154.25 |
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H.S CODE |
2930.90.4950 |
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SMILES |
C([C@@H]([C@@H](CS)O)O)S |
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CLASSIFICATION |
Disulfide bridge cleavage reagent, Reducing reagent |
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EXTRA NOTES |
A compound that, along with its isomer, Cleland's reagent (DITHIOTHREITOL), is used for the protection of sulfhydryl groups against oxidation to disulfides and for the reduction of disulfides to sulfhydryl groups. |
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| PHYSICAL AND CHEMICAL PROPERTIES | |
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PHYSICAL STATE. |
White crystalline powder |
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MELTING POINT |
82 ~ 86 C |
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BOILING POINT |
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DENSITY |
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SOLUBILITY IN WATER |
15.4 g/l |
| SOLVENT SOLUBILITY |
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VAPOR DENSITY |
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log P(octanol-water) |
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VAPOR PRESSURE |
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AUTOIGNITION TEMP |
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| pH |
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REFRACTIVE INDEX |
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FLASH POINT |
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| STABILITY AND REACTIVITY | |
| STABILITY | Stable under normal conditions. |
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INCOMPATIBLE MATERIALS |
Strong oxidizing agents, strong bases, strong reducing agents. |
| POLYMERIZATION |
Has not been reported |
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NFPA RATINGS |
Health: 0, Flammability: 1, Reactivity: 0 |
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| EXTERNAL LINKS & GENERAL DESCRIPTION |
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Wikipedia Linking - Dithioerythritol Google Scholar Search - Dithioerythritol Drug Information Portal (U.S. National Library of Medicine) - Dithioerythritol PubChem Compound Summary - Dithioerythritol KEGG (Kyoto Encyclopedia of Genes and Genomes) - Dithioerythritol Chemical Entities of Biological Interest (ChEBI) - Dithioerythritol http://www.ncbi.nlm.nih.gov/ - Dithioerythritol |
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| SALES SPECIFICATION | |
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APPEARANCE |
White crystalline powder |
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PURITY |
99.0% min (HPLC) |
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WATER |
1.0% max |
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MELTING POINT |
82 ~ 88 C |
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| TRANSPORT & REGULATORY INFORMATION | |
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UN NO. |
3335 |
| HAZARD CLASS |
9 |
| PACKING GROUP | III |
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| SAFETY INFORMATION | |
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HAZARD OVERVIEW |
OSHA Hazards:Target Organ Effect, Irritant. Target Organs: Central nervous system. Eyes: Causes eye irritation. Skin: May be harmful if absorbed through skin. Causes skin irritation. Inhalation: May be harmful if inhaled. Causes respiratory tract irritation. Ingestion: May be harmful if swallowed. |
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GHS |
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SIGNAL WORD |
Warning |
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PICTOGRAMS |
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HAZARD STATEMENTS |
H315-H319-H335 |
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P STATEMENTS |
P261-P305 + P351 + P338 |
| EC DIRECTIVES |
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| HAZARD CODES |
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RISK PHRASES |
36/37/38 |
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SAFETY PHRASES |
24/25-26-28-36/37/39 |
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| PACKING |
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Preserve in light-resistant and well-closed containers |
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| PRICE INFORMATION |