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LUPEOL |
| Synonyms. Lupeol; 20(29)-Lupen-3β-ol; 3beta-Hydroxy-20(29)-lupene; (3-beta)-Lup-20(29)-en-3-ol; Clerodol; Triterpene lupeol; beta-Viscol; Fagarasterol; |
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| PRODUCT IDENTIFICATION | |
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CAS RN |
545-47-1 |
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EINECS RN |
208-889-9 |
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FORMULA |
C30H50O |
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MOLE WEIGHT |
426.72 |
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H.S CODE |
2906.19.5000 |
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SMILES |
C1([ C@@ H]2CC[C@@]3([C@@]4([C@@H]([C@H]5[C@H](C(=C )C)C C[C@@]5(CC4)C)CC[C@H]3[C@@]2(CC[C@@H]1O)C)C)C)(C)C |
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CLASSIFICATION |
Triterpenoid, Anti-Inflammatory |
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EXTRA NOTES |
Lupeol is a pharmacologically active triterpenoid found in a variety of plants, including mango and acacia visco. It has several medicinal properties, one being anti-inflammatory. A 1998 study found lupeol to decrease paw swelling in rats by 39%, compared to 35% for the standardized control compound indomethacin. (Wikipedia) |
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| PHYSICAL AND CHEMICAL PROPERTIES | |
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PHYSICAL STATE. |
white powder |
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MELTING POINT |
216 C |
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BOILING POINT |
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DENSITY |
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SOLUBILITY IN WATER |
Insoluble |
| SOLVENT SOLUBILITY | Freely soluble in ether, benzene, petroleum ether, warm alcohol. |
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VAPOR DENSITY |
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log P(octanol-water) |
9.23 |
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VAPOR PRESSURE |
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AUTOIGNITION TEMP |
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| pK |
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REFRACTIVE INDEX |
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FLASH POINT |
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| STABILITY AND REACTIVITY | |
| STABILITY | Stable under normal conditions. |
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INCOMPATIBLE MATERIALS |
Strong oxidizing agents. |
| POLYMERIZATION |
Has not been reported |
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NFPA RATINGS |
Health: 1, Flammability: 0, Reactivity: 0 |
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| EXTERNAL LINKS & GENERAL DESCRIPTION |
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Wikipedia Linking - Lupeol Google Scholar Search - Lupeol Drug Information Portal (U.S. National Library of Medicine) - Lupeol PubChem Compound Summary - Lupeol KEGG (Kyoto Encyclopedia of Genes and Genomes) - Lupeol http://www.ebi.ac.uk/ - Lupeol http://www.ncbi.nlm.nih.gov/ - Lupeol http://toxnet.nlm.nih.gov/ |
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| SALES SPECIFICATION | |
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APPEARANCE |
white powder |
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ASSAY |
98.0% min |
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LOSS ON DRYING |
3.0% max |
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OPTICAL ROTATION |
+26.0° ~ +28.0° (c = 4.8 in chloroform) |
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HEAVY METALS |
20ppm max |
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| TRANSPORT & REGULATORY INFORMATION | |
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UN NO. |
Not regulated |
| HAZARD CLASS |
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| PACKING GROUP | |
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| SAFETY INFORMATION | |
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HAZARD OVERVIEW |
May be harmful if inhaled. May cause respiratory tract irritation. May be harmful if absorbed through skin. May cause skin irritation. May cause eye irritation. May be harmful if swallowed. |
| HAZARD CODES |
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RISK PHRASES |
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SAFETY PHRASES |
24/25 |
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| PACKING |
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Preserve in light-resistant and well-closed containers |