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OLEANDRIN |
| Synonyms. Oleandrin; 16beta-Acetoxy-3beta-(2,6-dideoxy-3-O-methyl-L-arabino- hexopyranosyloxy) -14 -hydroxycard-20(22)-enolide; (3beta,16beta)-16-(Acetyloxy)-3-((2,6-dideoxy-3-O-methyl-L- arabino- hexopyranosyl) oxy)-14-hydroxy card-20(22)-enolide; Neriol; Neriostene; Oleandrine; Oleandrina; Corrigen; Foliandrin; Folinerin; |
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| PRODUCT IDENTIFICATION | |
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CAS RN |
465-16-7 |
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EINECS RN |
207-361-5 |
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FORMULA |
C32H48O9 |
|
MOLE WEIGHT |
576.72 |
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H.S CODE |
2938.90.0000 |
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SMILES |
[C@@]12([C@@]([C@H]([C@H](C2)OC(=O)C)C2=CC(=O)OC2)(CCC 2 [C@H]1CC[C@H]1[C@@]2(CC[C@@H](C1)O[C@H]1C[C@@H] ([C@H] ([C@@H](O1)C)O)OC)C)C)O |
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CLASSIFICATION |
Triterpenoid, Cardiotonic, Diuretic, Steroid |
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EXTRA NOTES |
Oleandrin is a toxic cardiac glycoside found in oleander (Nerium oleander L.). Along with neandrin it is primarily responsible for the toxicity of the sap of oleander. Oleandrin has been used for many years in China and Russia for its properties as a cardiac glycoside, for both suicidal and therapeutic purposes as in treatment of cardiac insufficiency.(Wikipedia) |
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| PHYSICAL AND CHEMICAL PROPERTIES | |
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PHYSICAL STATE. |
white powder |
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MELTING POINT |
250 C |
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BOILING POINT |
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DENSITY |
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SOLUBILITY IN WATER |
Practically insoluble (2.68 mg/l) |
| SOLVENT SOLUBILITY | Soluble in alcohol, chloroform. |
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VAPOR DENSITY |
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log P(octanol-water) |
2.53 |
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VAPOR PRESSURE |
3.61E-19 mm Hg |
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AUTOIGNITION TEMP |
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| pK |
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REFRACTIVE INDEX |
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FLASH POINT |
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| STABILITY AND REACTIVITY | |
| STABILITY | Stable under normal conditions. |
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INCOMPATIBLE MATERIALS |
Strong oxidizing agents. |
| POLYMERIZATION |
Has not been reported |
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NFPA RATINGS |
Health: 1, Flammability: 0, Reactivity: 0 |
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| EXTERNAL LINKS & GENERAL DESCRIPTION |
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Wikipedia Linking - Oleandrin Google Scholar Search - Oleandrin Drug Information Portal (U.S. National Library of Medicine) - Oleandrin PubChem Compound Summary - Oleandrin Drug Bank - Oleandrin KEGG (Kyoto Encyclopedia of Genes and Genomes) - Oleandrin http://www.ebi.ac.uk/ - Oleandrin http://www.ncbi.nlm.nih.gov/ - Oleandrin http://toxnet.nlm.nih.gov/ |
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| SALES SPECIFICATION | |
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APPEARANCE |
white powder |
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ASSAY |
98.0% min (on anhydrous basis) |
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OPTICAL ROTATION |
-46.0° ~ -50.0° (c = 1.3 in MeOH) |
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HEAVY METALS |
20ppm max |
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| TRANSPORT & REGULATORY INFORMATION | |
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UN NO. |
2811 |
| HAZARD CLASS |
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| PACKING GROUP | |
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| SAFETY INFORMATION |
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HAZARD OVERVIEW |
May be harmful if inhaled. May cause respiratory tract irritation. May be harmful if absorbed through skin. May cause skin irritation. May cause eye irritation. May be harmful if swallowed. |
| HAZARD CODES |
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RISK PHRASES |
36/37/38 |
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SAFETY PHRASES |
26-36 |
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| PACKING |
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Preserve in light-resistant and well-closed containers |