OROXYLIN A

Synonyms. Oroxylin A; 5,7-Dihydroxy-6-methoxy-2-phenylchromen-4-one; 5,7-Dihydroxy-6-methoxy-2- phenyl-4H-1-benzopyran-4-one;

OROXYLIN A

Click for original image

 

PRODUCT IDENTIFICATION

CAS RN

480-11-5

EINECS RN

 

FORMULA

 C16H12O5

MOLE WEIGHT

284.26

H.S CODE

 2932.99.6100

SMILES

 c1(cc(c2c(o1)cc(c(c2O)OC)O)=O)c1ccccc1

CLASSIFICATION

Flavone, Resorcinol

EXTRA NOTES

 Oroxylin A is an O-methylated flavone, a chemical compound that can be found in the medicinal plant Scutellaria baicalensis[1] and the Oroxylum indicum tree(Wikipedia)

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE.

white powder

MELTING POINT

203 ~ 204 C

BOILING POINT

 

DENSITY

 

SOLUBILITY IN WATER

 

SOLVENT SOLUBILITY  

VAPOR DENSITY

 

log P(octanol-water)

 2.764

VAPOR PRESSURE

  

AUTOIGNITION TEMP

  
pH

 

REFRACTIVE INDEX

 

FLASH POINT

 

 

STABILITY AND REACTIVITY
STABILITY Stable under normal conditions.

INCOMPATIBLE MATERIALS

Strong oxidizing agents, Strong bases, moisture

POLYMERIZATION

Has not been reported

NFPA RATINGS

Health: 1, Flammability:0, Reactivity: 0

 

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking - Oroxylin A

Google Scholar Search - Oroxylin A

Drug Information Portal (U.S. National Library of Medicine) - Oroxylin A

PubChem Compound Summary - Oroxylin A

KEGG (Kyoto Encyclopedia of Genes and Genomes) - Oroxylin A

http://www.ebi.ac.uk/ - Oroxylin A

http://www.ncbi.nlm.nih.gov/ - Oroxylin A

SigmaAldrich
Oroxylin A is a flavonoid isolated from Scutellaria baicalensis, which is one of the most important medicinal herbs in traditional Korean/Chinese/Japanese medicine. The amelioration of Abeta(25-35) peptide-induced memory impairment by oroxylin A is believed to be mediated via the GABAergic neurotransmitter system after a single administration, or by reductions in Abeta(25-35) peptide-induced astrocyte and microglia activations, iNOS expression, lipid peroxidation, and increased cholinergic neurotransmission after subchronic administration.

 

SALES SPECIFICATION

APPEARANCE

white powder

CONTENT

98.0% min

LOSS ON DRYING

5.0% max

HEAVY METALS

20ppm max

MELTING POINT

203 ~ 204 C

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

Not regulated

HAZARD CLASS

  
PACKING GROUP  

 

SAFETY INFORMATION

HAZARD OVERVIEW

May be harmful if inhaled. May cause respiratory tract irritation. Harmful if absorbed through skin. May cause skin irritation. May cause eye irritation. Harmful Harmful by ingestion.

GHS

  

SIGNAL WORD

Warning

PICTOGRAMS

HAZARD STATEMENTS

H302

P STATEMENTS

 

EC DIRECTIVES

 

HAZARD CODES

Xn

RISK PHRASES

22

SAFETY PHRASES

 26-36

 

PACKING

Preserve in light-resistant and well-closed containers