PICEATANNOL

PRODUCT IDENTIFICATION
CAS NO. 10083-24-6, 21100-92-5

PICEATANNOL 

EINECS NO.  
FORMULA C14H12O4
MOL WT. 244.24

H.S. CODE

 2907.29.9000

TOXICITY

  
SYNONYMS Piceatannol; 3,5,3',4'-Tetrahydroxystilbene;
5-[2-(3,4-Dihydroxyphenyl)ethenyl]benzene-1,3-diol; 3'-Hydroxyresveratol; Demethyl isorhapontigenin; 3,3',4',5-Tetrahydroxystilbene; 3,3',4,5'-Tetrahydroxy stilbene; 3,5,3',4'-Tetrahydroxystilbene; Astringinin; 3,5,3',4'-Tetrahydroxy-trans-stilbene; (E)-4-(2-(3,5-Dihydroxyphenyl)ethenyl)-1,2-benzenediol; Piceatanol;
SMILES

c1(c(ccc(\C=C\c2cc(O)cc(c2)O)c1)O)O

CLASSIFICATION

Stilbenoid antioxidant

EXTRA NOTES

 Biochem/physiol Actions:A plant metabolite possessing anti-leukemic activity; inhibits the non-receptor kinases, Syk and Lck.

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE

off-white crystalline powder

MELTING POINT

226 - 230 C

BOILING POINT  
SPECIFIC GRAVITY  
SOLUBILITY IN WATER 0.5 mg/ml (
SOLVENT SOLUBILITY DMSO: 10 mg/ml, ethanol: 10 mg/ml
pH  
VAPOR DENSITY  

AUTOIGNITION

 

NFPA RATINGS

 Health hazard: 0, Fire: 0, Reactivity Hazard: 0

REFRACTIVE INDEX

 

FLASH POINT

 

STABILITY Stable under ordinary conditions.

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking - Piceatannol

Google Scholar Search - Piceatannol

Drug Information Portal (U.S. National Library of Medicine) - Piceatannol

PubChem Compound Summary - Piceatannol

Drug Bank -  Piceatannol

KEGG (Kyoto Encyclopedia of Genes and Genomes) - Piceatannol

http://www.ebi.ac.uk/ - Piceatannol

http://www.ncbi.nlm.nih.gov/ - Piceatannol

http://toxnet.nlm.nih.gov/
Hazardous Substances Data Bank - Piceatannol

Local:
Resveratrol (3,5,4'-trihydroxystilbene) is a non-flavonoid polyphenolics compound found highly in the skin of red grapes and as a constituent of red wine. It is also found in teas, berries and peanuts. Resveratrol is a compound of stilbene structure (and is responsible for the principle coloring of the plants. Resveratrol is created by plants as a phytoalexin (plant's defense arsenal) against bacteria and fungi. It is marketed as a nutritional supplement that shows health-giving antioxidant effects such as anti-cancer, antiviral, and anti-aging. Resveratrol inhibits COX-1 enzyme and demonstrates anti-inflammatory effects. It is a platelet aggregation inhibitor to block the adhesion of blood cells to vessel walls and therefore prevents heart disease and cerebral apoplexy.  It exists as two structural isomers: cis- (Z) and trans- (E),

Piceatannol or 3,4,3',5'-tetrahydroxy-trans-stilbene is a phenolic that is structurally related to resveratrolPiceatannol has one more hydroxyl group at 3' position. It is a metabolite of resveratrol and is found in red wine. Pterostilbene (3,5-Dimethoxy-4'-hydroxy-trans-stilbene) is an analog of resveratrol. The two phenolic hydroxyl groups among three are converted to methyl ethers. Some reports say that the ethers enhance antioxidant effects.

SALES SPECIFICATION

APPEARANCE

off-white crystalline powder
ASSAY

98.0% min (HPLC)

LOSS ON DRYING

0.5% max

ASH

0.1% max

HEAVY METALS

20ppm max

MICROBIOLOGICAL TEST

Total Plate Count: 1000CFU/G max
Mold and Yeast: 100CFU/G max
E.coli: Non-detective
Salmonella: Non-detective
TRANSPORTATION
PACKING
 
HAZARD CLASS  
UN NO. Nor regulated
SAFETY INFORMATION

HAZARD OVERVIEW

Not known
EC DIRECTIVES

 
HAZARD CODES

 

RISK PHRASES

 

SAFETY PHRASES

24/25