RANITIDINE

Synonyms. Ranitidine; Achedos; Acidex; Atural; Axoban; Coralen; Curan; Duractin; Ezopta; Gastrial; Gastrosedol; Istomar; Logast; Mauran; N-(2-((5-((Dimethylamino)methyl)furfuryl)thio) ethyl)-N'-methyl-2-nitro-1,1-ethenediamine; Microtid; Ptinolin; Quantor; Quicran; Radinat; Randin; Ranidine; Raniter; Ranitidina; Ranitidinum; Ranitiget; Rantacid; Raticina; Sampep; Urantac; Verlost; Vesyca; Vizerul; Weichilin; Weidos; Xanidine; Zantab; Zantadin;

RANITIDINE

 

PRODUCT IDENTIFICATION

CAS RN

66357-35-5(parent), 66357-59-3, 71130-06-8 (HCl)

EINECS RN

266-332-5 (parent), 266-333-0 (HCl)

FORMULA

C13H22N4O3S·HCl

MOLE WEIGHT

350.86

H.S CODE

2932.19.5000

SMILES

c1(oc(CSCCN\C(=C\[N+](=O)[O-])NC)cc1)CN(C)C

CLASSIFICATION

Histamine H2 receptor antagonist, Gastrointestinal agent, Anti-ulcer agent.

EXTRA NOTES

A non-imidazole blocker of those histamine receptors that mediate gastric secretion (H2 receptors). It is used to treat gastrointestinal ulcers.

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE.

white powder

MELTING POINT

69 ~ 70 C

BOILING POINT

 

DENSITY

 

SOLUBILITY IN WATER

2.47E+04

SOLVENT SOLUBILITY  

VAPOR DENSITY

 

log P(octanol-water)

0.27

VAPOR PRESSURE

 

AUTOIGNITION TEMP

 
pH

4.5 ~ 6.0

REFRACTIVE INDEX

 

FLASH POINT

 

 

STABILITY AND REACTIVITY
STABILITY Stable under normal conditions.

INCOMPATIBLE MATERIALS

Strong oxidizing agents

POLYMERIZATION

Has not been reported

NFPA RATINGS

Health: 2, Flammability:0, Reactivity: 0

 

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking - Ranitidine

Google Scholar Search - Ranitidine

Drug Information Portal (U.S. National Library of Medicine) - Ranitidine

PubChem Compound Summary - Ranitidine

Drug Bank - Ranitidine

KEGG (Kyoto Encyclopedia of Genes and Genomes) - Ranitidine

http://www.ebi.ac.uk/ - Ranitidine

http://www.ncbi.nlm.nih.gov/ - Ranitidine

http://otcsafety.org/
Ranitidine is an acid reducer available in over-the-counter (OTC) medicines that relieves or prevents heartburn symptoms associated with acid indigestion and sour stomach. It may be written as ranitidine or ranitidine hydrochloride, but it is the same active ingredient. Ranitidine is part of a group of acid reducers called histamine-2 antagonists, or H2 blockers. Ranitidine is approved by the U.S. Food and Drug Administration (FDA) and is safe and effective when used according to label directions. If you have kidney disease, you should not use an OTC medicine containing ranitidine, unless you are under the advice and supervision of a doctor.

 

SALES SPECIFICATION

APPEARANCE

white powder

ASSAY

98.0% ~ 102.0%

LOSS ON DRYING

0.5% max

IMPURITY

0.5% max (Total), 0.3% max (Individual)

pH

4.5 ~ 6.0

HEAVY METALS

20ppm max

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

Not regulated

HAZARD CLASS

 
PACKING GROUP  

 

SAFETY INFORMATION

HAZARD OVERVIEW

Target Organ Effect. Target Organs: Liver, Kidney, Heart, Nerves., Gastrointestinal tract

RISK PHRASES

 

SAFETY PHRASES

 

 

PACKING

 

 

PRICE INFORMATION