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RANITIDINE |
| Synonyms. Ranitidine; Achedos; Acidex; Atural; Axoban; Coralen; Curan; Duractin; Ezopta; Gastrial; Gastrosedol; Istomar; Logast; Mauran; N-(2-((5-((Dimethylamino)methyl)furfuryl)thio) ethyl)-N'-methyl-2-nitro-1,1-ethenediamine; Microtid; Ptinolin; Quantor; Quicran; Radinat; Randin; Ranidine; Raniter; Ranitidina; Ranitidinum; Ranitiget; Rantacid; Raticina; Sampep; Urantac; Verlost; Vesyca; Vizerul; Weichilin; Weidos; Xanidine; Zantab; Zantadin; |
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| PRODUCT IDENTIFICATION | |
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CAS RN |
66357-35-5(parent), 66357-59-3, 71130-06-8 (HCl) |
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EINECS RN |
266-332-5 (parent), 266-333-0 (HCl) |
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FORMULA |
C13H22N4O3S·HCl |
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MOLE WEIGHT |
350.86 |
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H.S CODE |
2932.19.5000 |
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SMILES |
c1(oc(CSCCN\C(=C\[N+](=O)[O-])NC)cc1)CN(C)C |
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CLASSIFICATION |
Histamine H2 receptor antagonist, Gastrointestinal agent, Anti-ulcer agent. |
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EXTRA NOTES |
A non-imidazole blocker of those histamine receptors that mediate gastric secretion (H2 receptors). It is used to treat gastrointestinal ulcers. |
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| PHYSICAL AND CHEMICAL PROPERTIES | |
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PHYSICAL STATE. |
white powder |
MELTING POINT |
69 ~ 70 C |
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BOILING POINT |
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DENSITY |
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SOLUBILITY IN WATER |
2.47E+04 |
| SOLVENT SOLUBILITY | |
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VAPOR DENSITY |
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log P(octanol-water) |
0.27 |
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VAPOR PRESSURE |
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AUTOIGNITION TEMP |
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| pH |
4.5 ~ 6.0 |
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REFRACTIVE INDEX |
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FLASH POINT |
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| STABILITY AND REACTIVITY | |
| STABILITY | Stable under normal conditions. |
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INCOMPATIBLE MATERIALS |
Strong oxidizing agents |
| POLYMERIZATION |
Has not been reported |
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NFPA RATINGS |
Health: 2, Flammability:0, Reactivity: 0 |
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| EXTERNAL LINKS & GENERAL DESCRIPTION |
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Wikipedia Linking - Ranitidine Google Scholar Search - Ranitidine Drug Information Portal (U.S. National Library of Medicine) - Ranitidine PubChem Compound Summary - Ranitidine Drug Bank - Ranitidine KEGG (Kyoto Encyclopedia of Genes and Genomes) - Ranitidine http://www.ebi.ac.uk/ - Ranitidine http://www.ncbi.nlm.nih.gov/ - Ranitidine http://otcsafety.org/Ranitidine is an acid reducer available in over-the-counter (OTC) medicines that relieves or prevents heartburn symptoms associated with acid indigestion and sour stomach. It may be written as ranitidine or ranitidine hydrochloride, but it is the same active ingredient. Ranitidine is part of a group of acid reducers called histamine-2 antagonists, or H2 blockers. Ranitidine is approved by the U.S. Food and Drug Administration (FDA) and is safe and effective when used according to label directions. If you have kidney disease, you should not use an OTC medicine containing ranitidine, unless you are under the advice and supervision of a doctor. |
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| SALES SPECIFICATION | |
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APPEARANCE |
white powder |
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ASSAY |
98.0% ~ 102.0% |
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LOSS ON DRYING |
0.5% max |
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IMPURITY |
0.5% max (Total), 0.3% max (Individual) |
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pH |
4.5 ~ 6.0 |
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HEAVY METALS |
20ppm max |
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| TRANSPORT & REGULATORY INFORMATION |
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UN NO. |
Not regulated |
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| SAFETY INFORMATION |
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HAZARD OVERVIEW |
Target Organ Effect. Target Organs: Liver, Kidney, Heart, Nerves., Gastrointestinal tract |
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RISK PHRASES |
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SAFETY PHRASES |
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| PACKING |
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| PRICE INFORMATION |
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