SCUTELLARIN

Synonyms. Scutellarin; Breviscapin; Scutellarein-7-O-beta-D-glucuronide; Scutellarein-7-glucuronide; Scutellarein-7beta-D-glucuronide; Scutellarein-7beta-D-glucuronoside; Breviscapine; Scutellarein-7-glucuronide; 5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl-beta-D- glucopyranosiduronic acid; 7-(beta-D-Glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)- 4H-1-benzopyran-4-one;

SCUTELLARIN

Click for original image

 

PRODUCT IDENTIFICATION

CAS RN

27740-01-8

EINECS RN

 

FORMULA

C21H18O12

MOLE WEIGHT

462.36

H.S CODE

2938.90.0000

SMILES

O([C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O1)C(=O)O) c1cc2c(c (cc (o2) c2ccc(cc2)O)=O)c(c1O)O

CLASSIFICATION

Flavone glycoside

EXTRA NOTES

Scutellarin is a flavonoid that exhibits a number of cardio- and neuro-protective effects. Scutellarin inhibits p38 activity, ERK phosphorylation, and TGF-β expression and fibrosis in a rat myocardial infarct model. In a cerebral ischemia-reperfusion model, the compound reduced infarct volume and neurological deficits by increasing eNOS expression while inhibiting the induction of iNOS. (SigmaAldrich)
Other RN: 1329-06-2, 32647-60-2, 676536-34-8

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE.

light yellow power

MELTING POINT

> 300 C

BOILING POINT

 

DENSITY

 

SOLUBILITY IN WATER

Practically insoluble

SOLVENT SOLUBILITY

Soluble in alkali hydroxides, glacial acetic acid. Slightly soluble in organic solvents.

VAPOR DENSITY

 

log P(octanol-water)

 

VAPOR PRESSURE

 

AUTOIGNITION TEMP

 
pH

 

REFRACTIVE INDEX

 

FLASH POINT

 

 

STABILITY AND REACTIVITY
STABILITY Stable under normal conditions.

INCOMPATIBLE MATERIALS

Strong oxidizing agents

POLYMERIZATION

Has not been reported

NFPA RATINGS

Health: 0, Flammability:0, Reactivity: 0

 

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking - Scutellarin

Google Scholar Search - Scutellarin

Drug Information Portal (U.S. National Library of Medicine) - Scutellarin

PubChem Compound Summary - Scutellarin

KEGG (Kyoto Encyclopedia of Genes and Genomes) - Scutellarin

http://www.ebi.ac.uk/ - Scutellarin

http://www.ncbi.nlm.nih.gov/ - Scutellarin

 

SALES SPECIFICATION

APPEARANCE

light yellow power

CONTENT

98.0% min

LOSS ON DRYING

1.0% max

HEAVY METALS

20ppm max

OPTICAL ROTATION

-11.0° ~ 17.0° (in water)

MELTING POINT

265 ~ 280 C

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

Not regulated

HAZARD CLASS

 
PACKING GROUP  

 

SAFETY INFORMATION

HAZARD OVERVIEW

May be harmful if inhaled. May cause respiratory tract irritation. May be harmful if absorbed through skin. May cause skin irritation. May cause eye irritation. May be harmful if swallowed. OSHA Hazards: Not known

EC DIRECTIVES

 

HAZARD CODES

 

RISK PHRASES

 

SAFETY PHRASES

 

 

PACKING

Preserve in light-resistant and well-closed containers