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SCUTELLARIN |
| Synonyms. Scutellarin; Breviscapin; Scutellarein-7-O-beta-D-glucuronide; Scutellarein-7-glucuronide; Scutellarein-7beta-D-glucuronide; Scutellarein-7beta-D-glucuronoside; Breviscapine; Scutellarein-7-glucuronide; 5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl-beta-D- glucopyranosiduronic acid; 7-(beta-D-Glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)- 4H-1-benzopyran-4-one; |
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| PRODUCT IDENTIFICATION | |
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CAS RN |
27740-01-8 |
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EINECS RN |
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FORMULA |
C21H18O12 |
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MOLE WEIGHT |
462.36 |
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H.S CODE |
2938.90.0000 |
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SMILES |
O([C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O1)C(=O)O) c1cc2c(c (cc (o2) c2ccc(cc2)O)=O)c(c1O)O |
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CLASSIFICATION |
Flavone glycoside |
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EXTRA NOTES |
Scutellarin is a flavonoid that exhibits a number of cardio- and neuro-protective effects. Scutellarin inhibits p38 activity, ERK phosphorylation, and TGF-β expression and fibrosis in a rat myocardial infarct model. In a cerebral ischemia-reperfusion model, the compound reduced infarct volume and neurological deficits by increasing eNOS expression while inhibiting the induction of iNOS.
(SigmaAldrich) Other RN: 1329-06-2, 32647-60-2, 676536-34-8 |
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| PHYSICAL AND CHEMICAL PROPERTIES | |
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PHYSICAL STATE. |
light yellow power |
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MELTING POINT |
> 300 C |
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BOILING POINT |
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DENSITY |
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SOLUBILITY IN WATER |
Practically insoluble |
| SOLVENT SOLUBILITY | Soluble in alkali hydroxides, glacial acetic acid. Slightly soluble in organic solvents. |
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VAPOR DENSITY |
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log P(octanol-water) |
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VAPOR PRESSURE |
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AUTOIGNITION TEMP |
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| pH |
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REFRACTIVE INDEX |
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FLASH POINT |
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| STABILITY AND REACTIVITY | |
| STABILITY | Stable under normal conditions. |
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INCOMPATIBLE MATERIALS |
Strong oxidizing agents |
| POLYMERIZATION |
Has not been reported |
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NFPA RATINGS |
Health: 0, Flammability:0, Reactivity: 0 |
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| EXTERNAL LINKS & GENERAL DESCRIPTION |
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Wikipedia Linking - Scutellarin Google Scholar Search - Scutellarin Drug Information Portal (U.S. National Library of Medicine) - Scutellarin PubChem Compound Summary - Scutellarin KEGG (Kyoto Encyclopedia of Genes and Genomes) - Scutellarin http://www.ebi.ac.uk/ - Scutellarin http://www.ncbi.nlm.nih.gov/ - Scutellarin |
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| SALES SPECIFICATION | |
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APPEARANCE |
light yellow power |
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CONTENT |
98.0% min |
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LOSS ON DRYING |
1.0% max |
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HEAVY METALS |
20ppm max |
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OPTICAL ROTATION |
-11.0° ~ 17.0° (in water) |
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MELTING POINT |
265 ~ 280 C |
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| TRANSPORT & REGULATORY INFORMATION | |
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UN NO. |
Not regulated |
| HAZARD CLASS |
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| PACKING GROUP | |
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| SAFETY INFORMATION | |
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HAZARD OVERVIEW |
May be harmful if inhaled. May cause respiratory tract irritation. May be harmful if absorbed through skin. May cause skin irritation. May cause eye irritation. May be harmful if swallowed. OSHA Hazards: Not known |
| EC DIRECTIVES |
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| HAZARD CODES |
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RISK PHRASES |
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SAFETY PHRASES |
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| PACKING |
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Preserve in light-resistant and well-closed containers |