SULFADIAZINE SODIUM

PRODUCT IDENTIFICATION

CAS NO. 547-32-0 (Sodium); 68-35-9 (base)

SULFADIAZINE

EINECS NO. 208-919-0; 200-685-8
FORMULA C10H9N4NaO2S
MOL WT. 272.26

H.S. CODE

 

TOXICITY

 
SYNONYMS Sodium, (N(1)-2-pyrimidinylsulfanilamido)-;
2-Sulfanilamidopyrimidine sodium salt; Benzenesulfonamide, 4-amino-N-2-pyrimidinyl-, monosodium salt; Monosodium 2-sulfanilamidopyrimidine; N(1)-2-Pyrimidinylsulfanilamide monosodium salt; N1-2-Pyrimidinylsulfanilamide monosodium salt; Solfadiazina sodica; Soluble sulfadiazine; Soludiazine; Sulfadiazin-natrium; Sulfadiazina sodica; Sulfadiazine sodique; Sulfadiazinum natricum; Sulfanilamide, Sulphadiazine; Suthogen; Benzenesulfonamide, 4-amino-N-2-pyrimidinyl-, monosodium salt; 2-Sulfanilamidopyrimidin; 2-Sulfanilamidopyrimidine; Adiazin; Adiazine; Cremodiazine; Cremotres; Debenal; Deltazina; Diazin; Diazolone; Diazovit; Diazyl; Eskadiazine; Liquadiazine; Metha-Meridiazine; Microsulfon; N(1)-2-Pyrimidinylsulfanilamide; Neazine; Neotrizine; Palatrize; Sodium sulfapyrimidine;
DERIVATION

 

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE white to off-white crystalline powder
MELTING POINT  
BOILING POINT

 

SPECIFIC GRAVITY  
SOLUBILITY IN WATER Soluble
pH  
VAPOR DENSITY

 

REFRACTIVE INDEX

 

NFPA RATINGS

 

AUTOIGNITION

 

FLASH POINT

 

STABILITY Stable under normal conditions.

GENERAL DESCRIPTION & APPLICATIONS

Sulfadiazine is a short-acting sulfonamide antibiotic used in the treatment of infections due to susceptible organisms, including nocardiosis, toxoplasmosis, otitis media caused by susceptible strains of Haemophilus influenzae, streptococci, and pneumococci, and falciparum malaria caused by chloroquine-resistant plasmodia. It eliminates bacteria by stopping the production of folic acid inside the bacterial cell, and is commonly used to treat urinary tract infections. It is frequently used in combination with other sulfonamides and pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections. Silver sulfadiazine (the silver derivative of sulfadiazine) is a topical antibacterial against many gram-positive and gram-negative organisms, as well as being effective against yeasts; used as a topical antiinfective for the prevention and treatment of second- and third-degree burns. The sodium salt of sulfadiazine has the same actions with the base and is administered intravenously.

SALES SPECIFICATION

APPEARANCE

white to off-white crystalline powder

ASSAY

99.0% min

ALKALINITY 9.5 - 10.5
COLOR OF SOLUTION Y3 max
SELENIUM 30ppm max
LOSS ON DRYING 0.5% max
RELATED MATTERS 0.5% max
TRANSPORTATION
PACKING
 
HAZARD CLASS  
UN NO.  
OTHER INFORMATION