beta-BOSWELLIC ACID

Synonyms. Boswellic acid; beta-Boswellic acid; (3alpha,4beta)-3-Hydroxyurs-12-en-23-oic acid; 12-Ursene-3,24-diol; (3R,4R,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bR)-3-Hydroxy-4,6a,6b,8a,11, 12,14b -heptamethyl-2,3,4a,5,6,7,8,9,10,11,12,12a,14, 14a-tetradecahydro-1H-picene-4-carboxylic acid

beta-BOSWELLIC ACID

Click for original image

 

PRODUCT IDENTIFICATION

CAS RN

631-69-6

EINECS RN

 

FORMULA

C30H48O3

MOLE WEIGHT

456.71

H.S CODE

2918.19.9000

SMILES

C1C[C@@]2([C@@H](CC[C@@]3([C@@H]2CC=C2[C@@]3(C)CC[C@@]3 (CC[C@H]([C@@H]([C@@H]23)C)C)C)C)[C@@](C)([C@@H] 1O)C(O)=O)C

CLASSIFICATION

Triterpenoid, Analgesic, Anti-Inflammatory, Antirheumatic

EXTRA NOTES

The boswellic acids are organic acids, consisting of a pentacyclic triterpene, a carboxyl group and at least one other functional group. Alpha-boswellic acid and beta-boswellic acid, C30H48O3 both have an additional hydroxyl group; they differ only in their triterpene structure. Acetyl-alpha-boswellic acid and acetyl-beta-boswellic acid, C32H50O4, replace the hydroxyl group with an acetyl group.(Wikipedia)
The beta-form is predominant in nature and is accompanied by small amounts of alpha- and gamma- forms

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE.

white powder

MELTING POINT

228 ~ 230 C

BOILING POINT

 

DENSITY

 

SOLUBILITY IN WATER

Practically insoluble

SOLVENT SOLUBILITY Soluble in alcohol, chloroform, ether, acetone. 100 ml of boiling methanol will dissolve 8 grams of beta-boswellic acid.

VAPOR DENSITY

 

log P(octanol-water)

 

VAPOR PRESSURE

 

AUTOIGNITION TEMP

 
pK

 

REFRACTIVE INDEX

 

FLASH POINT

 

 

STABILITY AND REACTIVITY
STABILITY Stable under normal conditions.

INCOMPATIBLE MATERIALS

Strong oxidizing agents.

POLYMERIZATION

Has not been reported

NFPA RATINGS

Health: 1, Flammability: 0, Reactivity: 0

 

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking - Boswellic acid

Google Scholar Search - Boswellic acid

Drug Information Portal (U.S. National Library of Medicine) - Boswellic acid

PubChem Compound Summary - Boswellic acid

KEGG (Kyoto Encyclopedia of Genes and Genomes) - Boswellic acid

http://www.ebi.ac.uk/ - Boswellic acid

http://www.ncbi.nlm.nih.gov/ - Boswellic acid

http://toxnet.nlm.nih.gov/
Hazardous Substances Data Bank - Boswellic acid

 

SALES SPECIFICATION

APPEARANCE

white powder

ASSAY

98.0% min (on anhydrous basis)

OPTICAL ROTATION

+105.0° ~ +109.0° (c = 0.75 in CHCl3)

HEAVY METALS

20ppm max

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

Not regulated

HAZARD CLASS

 
PACKING GROUP  

 

SAFETY INFORMATION

HAZARD OVERVIEW

May be harmful if inhaled. May cause respiratory tract irritation. May be harmful if absorbed through skin. May cause skin irritation. May cause eye irritation. May be harmful if swallowed.

HAZARD CODES

 

RISK PHRASES

36/37/38

SAFETY PHRASES

26-36

 

PACKING

Preserve in light-resistant and well-closed containers