5-METHYLISATIN

PRODUCT IDENTIFICATION
CAS NO. 608-05-9

5-METHYLISATIN
EINECS NO. 210-152-1
FORMULA C9H7NO2
MOL WT. 161.16
H.S. CODE  
TOXICITY  
SYNONYMS 5-Methylindole-2,3-dione;
5-methylindole-2,3(1H)-dione; 5-Metilindol-2,3(1H)-diona; 5-Methylindole-2,3(1H)-dione;
SMILES 
 

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE yellow to redish crystalline solid
MELTING POINT 240 - 246 C
BOILING POINT  
SPECIFIC GRAVITY  
SOLUBILITY IN WATER  

SOLVENT SOLUBILITY

  
AUTOIGNITION  
pH  
VAPOR DENSITY  
NFPA RATINGS  

REFRACTIVE INDEX

  
FLASH POINT

 
STABILITY Stable under ordinary conditions

GENERAL DESCRIPTION & APPLICATIONS
Isatin, an indole derivative, is a yellow to red needle crystalline solid; soluble in hot water. It is a hetero bicyclic aromatic compound with diketone at 2 and 3 positions. Isatin class compounds are mainly used as raw material in dye manufacturing (artificial indigo, disperse dye yellows). It has lactam (a cyclic amide) structure which is an important part of antibiotics, such as penicillin. Cyclic ester structures are active nucleuses in pharmacological activity and flavorings. They are used as intermediates for the synthesis of pharmaceuticals, herbicides, and other chemical compounds.
SALES SPECIFICATION

APPEARANCE

 yellow to reddish crystalline solid
ASSAY (G.C)

99.0% min

MELTING POINT 240 - 245 C
TRANSPORTATION
PACKING  
HAZARD CLASS  
UN NO.

 
OTHER INFORMATION
Hazard Symbols: XN, Risk Phrases: 22, Safety Phrases: 24/25

GENERAL DESCRIPTION OF INDOLE
Indole, benzopyrrole, is a yellow crystalline powder with unpleasant aroma. It has the pyrrole ring (five-membered unsaturated ring structure composed of four carbon atoms and one nitrogen atom) which is fused to benzene ring. There are tautomerer called indolenine (unsubstituted 3H-indole) and structural isomer, isoindole. But they are unstable. Indole occurs in some plants or in coal tar, and is formed in the intestine during putrefaction and by certain cultures of bacteria. it is commercially synthesized from phenylhydrazine and pyruvic acid.  Indole structure is a motif in nature. Prominent examples include tryptophan (aromatic side chain amino acid), serotonin (neurotransmitter), auxin (plant growth hormone), and indigo (plant colorant). One more interesting point is all these compounds have functional branches at 3 position. Indole is used in perfumery and in preparing tryptophan, one of the 20 amino acids commonly found in animal proteins. It has important application in the industry of plant growth. It is used to prepare indoleacetic acid (auxin) and other plant growth substances which help the development of roots in plant. It is used to make selective herbicides. Indole and its derivatives are widely used in making perfumes, dyes, agrochemicals and medicines.