PHTHALAZINE

PRODUCT IDENTIFICATION
CAS NO.

253-52-1

PHTHALAZINE
EINECS NO. 205-963-2
FORMULA C8H6N2
MOL WT. 130.15
H.S. CODE  
TOXICITY  
SYNONYMS Benzo[d]pyridazine; beta-Phenodiazine; 2,3-Benzodiazine;
2,3-Diazanaphthalene;
SMILES

 

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE yellow solid
MELTING POINT 89 - 92 C
BOILING POINT 315 - 317 C
SPECIFIC GRAVITY

 
SOLUBILITY IN WATER Soluble
pH  
VAPOR DENSITY  

AUTOIGNITION

 

NFPA RATINGS

  

REFRACTIVE INDEX

 
FLASH POINT

 
STABILITY Stable under ordinary conditions

GENERAL DESCRIPTION & APPLICATIONS
Quinazoline is a heterocyclic solid-ring structure compound containing a benzene fused to pyrimidine. There are four isomers which are identified by Nirtogen positions; Cinnoline (1,2-Benzodiazine; Benzo[c]pyridazine; 1,2-Diazanaphthalene, CAS #: 253-66-7), Phthalazine (2,3-Benzodiazine; Benzo[d]pyridazine, CAS #: 253-52-1), Quinazoline (1,3-Benzodiazine; Benzo[a]pyrimidine, CAS #: 253-82-7), and Quinoxaline (1,4-Benzodiazine; Benzo[a]pyrazine, CAS #: 91-19-0). They have bicyclic aromatic ring structures comprising a benzene ring linked to two-nitrogen containing aromatic ring such as pyridazine, pyrimidine, pyrazine. Examples of end products which have the fundamental structures of them are:
  • Cinnoline structure
    • Cintazone (non-steroidal anti-inflammatory agent)
    • Cinoxacin (quinolone class anti-infective agent)
  • Phthalazine structure
    • Hydralazine, Todralazine (Antihypertensives)
  • Quinazoline structure
    • Prazosin and Doxazosin (Adrenergic alpha-antagonists)
  • Quinoxaline structure
    • Sulfaquinoxaline (Anti-infective agent or Antiprotozoal agent)
    • Echinomycin (polypeptide antibiotic agent)

Diazanaphthalenes and their derivatives are used for making medicines such as anthelmintic, antiallergenic, anti-histamic, anti-emetic and anti-migraine agents. They are used as chemical intermediates for making fungicides and other organic compounds.

Luminol, a chemoluminescent dye, is a phthalazinedione derivative. Diazanaphthalenes can find applicaton in the luminescence (light emission), generated as the result of direct transformation of chemical energy into light energy without showing a corresponding degree of heat. Diazanaphthalenes can be the basic substance of fluorescent properties, used in luminescence chemistry of photosensitizing and organic electroluminescence materials industry which lead to the rapid development of photovoltaic and display devices.
SALES SPECIFICATION

APPEARANCE

 yellow solid
CONTENT

98.0% min
TRANSPORTATION
PACKING  
HAZARD CLASS  
UN NO.  
OTHER INFORMATION
Hazard Symbols: , Risk Phrases: , Safety Phrases: 24/25