THIOURACIL

PRODUCT IDENTIFICATION
CAS NO. 141-90-2

THIOURACIL

EINECS NO. 205-508-8
FORMULA C4H4N2OS
MOL WT. 128.15

H.S. CODE

  

TOXICITY

  
SYNONYMS 2-Thiouracil; 2,3-Dihydro-2-thioxo-4(1H)-pyrimidinone;
Tiouracyl; 2-Mercapto-4(1H)-pyrimidinone; 2-Mercapto-4-hydroxypyrimidine; 2-Mercapto-4-pyrimidinol; 2-Mercapto-4-pyrimidone; 2-TU; 2-Thio-1,3-pyrimidin-4-one; 2-Thio-2,4-(1H,3H)-pyrimidinedione; 2-Thio-4-oxo-1,3-pyrimidine; 2-Thio-4-oxypyrimidine; 2-Thio-6-oxypyrimidine; 4-Hydroxy-2(1H)-pyrimidinethione; 4-Hydroxy-2-mercaptopyrimidine; 4-Hydroxy-2-pyrimidinethiol; 6-Hydroxy-2-mercaptopyrimidine; Other CAS RN: 156-82-1; 4401-53-0; 4401-54-1; 107646-89-9; 107646-88-8;
SMILES  

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE white to pale yellow crystalline powder

MELTING POINT

 >300 C
BOILING POINT  
SPECIFIC GRAVITY  

SOLUBILITY IN WATER

 Insoluble (soluble in alkali)
pH  
VAPOR DENSITY  
AUTOIGNITION

 

REFRACTIVE INDEX

 

NFPA RATINGS  
FLASH POINT

 

STABILITY Stable under ordinary conditions.

GENERAL DESCRIPTION & APPLICATIONS

Thiouracil, a thiourea derivative, is the basic structure of several drugs used to treat hyperthyroidism. They It inhibit the synthesis of the thyroid hormones produced by the thyroid gland. They are used as antithyroid, coronary vasodilator, and in congestive heart failure. Thiouracil is replaced by other drugs as it is known to cause blood dyscrasias and suspected of terato- and carcinogenesis. In industry thiouracil is used in galvanization as a grain refining agent. Some derivatives of uracils, pyrimidines, thiazolines, and organodisulfides are used as grain refining agents in plating.

SALES SPECIFICATION

APPEARANCE

 white to pale yellow crystalline powder

PURITY

97.0% min

TRANSPORTATION
PACKING  
HAZARD CLASS  
UN NO.  
OTHER INFORMATION

Hazard Symbols: XN, Risk Phrases: 40, Safety Phrase: 36/37