2-HYDROXY-5-NITROANILINE

PRODUCT IDENTIFICATION
CAS NO. 99-57-0

2-HYDROXY-5-NITROANILINE

EINECS NO. 202-767-9
FORMULA H2NC6H3(NO2)OH
MOL WT. 154.13
H.S. CODE  
TOXICITY Oral rat LD50: 2400 mg/kg
SYNONYMS 2-Amino-4-nitrophenol; 1-Amino-2-Hydroxy-5-Nitrobenzene;
3-amino-4-hydroxynitrobenzene; p-nitro-o-aminophenol; C.I. 76530;
SMILES 
 

CLASSIFICATION

AROMATIC AMINES / NITRO COMPOUNDS / DYES /

PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE yellow crytal
MELTING POINT 143 - 145 C (decomposes)
BOILING POINT  
SPECIFIC GRAVITY  
SOLUBILITY IN WATER slightly soluble (Soluble in ether, acid)
AUTOIGNITION  
pH  
VAPOR DENSITY  
NFPA RATINGS  

REFRACTIVE INDEX

  
FLASH POINT

100 C

STABILITY Stable under ordinary conditions

APPLICATIONS
The prefix nitro- indicates the presence of NO2- radical, while nitrate refers to any salt or ester of nitric acid or the NO3- anion. Nitroso- is the prefix indicating presence of the group -NO and azo- is for -N=N- group. Some range of  organic compounds containing nitrogen include nitro compounds (RNO2 ), nitroso compounds (RNO), amines (R3N ), amino acids, and natural alkaloids or nucleotides. The nitrogen ion in nitro compounds is trigonally planar with 120° angles. There are two resonance bonds so that the two oxygens are equivalent. Nitro compounds are strongly basic due to electron withdrawing both inductively and mesomerically. Historically, they are abundant in dyes and explosives. Nitro compounds, organic hydrocarbons having one or more NO2 groups bonded via nitrogen to the carbon framework, are versatile intermediate in organic synthesis.
  • Michael addition
  • Reduction
  • Henry Reaction (Nitro-aldol reaction)
  • Nef reaction
  • O-Alkylation
  • Cycloaddition
  • Substitution, Elimination, Conversion reaction
  • Alkylation, Acylation, and Halogenation

One of the most important aromatic amines is aniline; pale brown liquid boiling at 184 C, melting at -6 C. Aniline is obtained commercially from chlorobenzene by heating  with ammonia in the presence of copper catalyst or from a product of coal tar (nitrobenzene) through the reduction reaction. Aniline is the starting material in the dye manufacturing industry and as in the manufacture of others. Aniline is converted into sulfanilic acid which is the parent compound of the sulfa drugs. Aniline is also important in the manufacture of rubber-processing chemicals, antioxidants and varnishes. Nitroanilines are used in the synthesis of dyes, agrochemicals, pharmaceuticals, rubber and plastic additives, photographic antifogging agents and coccidiostats. 2-Hydroxy-5-nitroaniline is used as an intermediate for pharmaceuticals, dyes 9especially reactive dyes), and other organic chemicals
SALES SPECIFICATION

APPEARANCE

 yellow crytal
ASSAY

98.0% min

MELTING POINT

138 C

TRANSPORTATION
PACKING 25kgs in drum
HAZARD CLASS  
UN NO.

 

REMARKS
Hazard Symbols: XN, Risk Phrases: 20/2122, Safety Phrases:28A/36/37/45