AVOBENZONE

PRODUCT IDENTIFICATION
CAS NO. 70356-09-1

AVOBENZONE

EINECS NO. 274-581-6
FORMULA C20H22O3
MOL WT. 310.39

H.S. CODE

 2914.50
TOXICITY

 
SMILES

 
SYNONYMS 4-tert-Butyl-4'-methoxy-dibenzoylmethane;
1-(4-tert-Butylphenyl)-3-(4-methoxyphenyl) 1,3-propanedione); 1-(4-(1,1-Dimethylethyl)phenyl)-3-(4-methoxyphenyl)-1,3-propanedione;

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE

White to off-white crystalline powder

MELTING POINT

 80 - 85 C
BOILING POINT  
SPECIFIC GRAVITY

1.037 - 1.041

SOLUBILITY IN WATER

 Insoluble
pH

 

VISCOSITY  
AUTOIGNITION

 

REFRACTIVE INDEX

 

NFPA RATINGS Health: 1; Flammability: 1; Instability: 0
FLASH POINT  
STABILITY Stable under normal conditions.

APPLICATIONS
Avobenzone having phenyl ketone group and sterically hindered group in one molecule, is an oil soluble sunscreen agent that absorbs a wider range of UV wavelengths. It absorbs both UV-A (380–315 nm that is associated with long term skin damage) and UV-B (315–280 nm that causes sunburn) rays. Avobenzone is known as one of the most effective sunscreen ingredient.

Benzophenone, an aromatic ketones (diphenyl ketone), is an important compound in organic photochemistry and perfumery as well as in organic synthesis. It is a white crystalline substance with rose-like odor; insolube in water; melting point 49 C; boiling point 305 - 306 C. Benzophenone is used as a constituent of synthetic perfumes and as a starting material for the manufacture of dyes, pesticides and drugs (especially anxiolytic and hypnotic drugs). Benzophenone is used as a photoinitiator of UV-curing applications in inks, adhesive and coatings, optical fiber as well as in printed circuit boards. Photoinitiators are compounds that break down into free radicals upon exposure to ultraviolet radiation. Photoinitiators undergo a unimolecular bond cleavage upon irradiation to yield free radicals (benzoin esters; benzil ketals; alpha-dialkoxy acetophenones; alpha-hydroxy alkylphenones; alpha-amino alkylphosphine; acylphosphine oxides). Another type of photoinitiators undergo a bimolecular reaction where the excited state of the photoinitiator interacts with a second molecule (a coinitiator) to generate free radicals (benzophenones, amines; thioxanthones, titanocenes). Ultraviolet radiation has more energy than visible light, and thus degrade the physical properties such as the appearance of organic substances and plastics. Benzophenones can act as optical filters or deactivate substrate molecules that have been excited by light for the protection polymers and organic substances. They, cosmetic grades, are used as sunscreen agents to reduce skin damage by blocking UV-A, B.

Chemical ingredients for sunscreen are;

  • p-Aminobenzoic acids
    • p-Aminobenzoic acid (CAS #: 150-13-0)
    • p-Aminobenzoic Acid, monoglyceryl Ester (CAS #: 136-44-7)
    • p-Aminobenzoic Acid, octyl dimethyl Ester (Padimate 0, CAS #: 21245-02-3)
    • p-Aminobenzoic Acid, ethyl dihydroxypropyl  (Roxadimate, CAS #: 58882-17-0)
    • p-Aminobenzoic Acid, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide ester
    • Octyl Triazone (CAS #: 88122-99-0)
    • p-Aminobenzoic Acid, PEG-25 (CAS #: 116242-27-4)
  • Anthranilates
    • Menthyl anthranilate (CAS #: 134-09-8)
  • Benzophenones
    • Benzophenone (CAS #: 119-61-9)
    • 2,4-Dihydroxybenzophenone (Benzophenone-1, CAS #: 131-56-6)
    • 2,2',4,4'-Tetrahydroxybenzophenone (Benzophenone-2, CAS #: 131-55-5)
    • 2-Hydroxy-4-methoxybenzophenone (Benzophenone-3, Oxybenzone, CAS #: 131-57-7)
    • 2-Hydroxy-4-methoxybenzophenone-5-sulfonic Acid (Benzophenone-4, Sulisobenzone, CAS #: 4065-45-6
    • 2-Hydroxy-4-methoxybenzophenone-5-sulfonic Acid, Monosodium Salt (Benzophenone-5, CAS #: 6628-37-1)
    • 2,2'-Dihydroxy-4,4'-dimethoxybenzophenone (Benzophenone-6, CAS #: 131-54-4)
    • 5-Chloro-2-hydroxybenzophenone  (Benzophenone-7, CAS #: 85-19-8)
    • 2,2'-Dihydroxy-4-methoxybenzophenone (Benzophenone-8, Dioxybenzone, CAS #: 131-53-3)
    • 2,2'-Dihydroxy-4,4'-dimethoxybenzophenone-5,5'-disulfonic Acid Sodium Salt (Benzophenone-9, CAS #: 76656-36-5)
    • 2-Hydroxy-4-methoxy-4'-methyl-benzophenone (Benzophenone-10, Mexenone, CAS #: 1641-17-4)
    • Bis(2,4-ihydroxyphenyl)Methanone (Benzophenone-11, CAS #: 1341-54-4)
    • 2-Hydroxy-4-(Octyloxy)Benzophenone (Benzophenone-12, Octabenzone, CAS #: 1843-05-6)
    • 2,2'-Dihydroxy-4-methoxybenzophenone [Dioxybenzone, CAS #: 131-53-3)
    • 2-Hydroxy-4-methoxybenzophenone (Oxybenzone, CAS #: 131-57-7)
    • 2-Hydroxy-4-methoxybenzophenone-5-sulphonic Acid  (Sulisobenzone, CAS #: 4065-45-6)
  • Camphors
    • Benzylidene Camphor Sulfonic Acid (CAS #: 56039-58-8)
    • 3-Benzylidene Camphor (CAS #: 15087-24-8)
    • Polyacrylamidomethyl Benzylidene Camphor (CAS #: 113783-61-2)
    • Terephthalylidene Dicamphor Sulfonic Acid (CAS #: 90457-82-2)
    • 3-(4-Methylbenzyliden)Camphor (CAS #: 36861-47-9)
    • Camphor Benzalkonium Methosulfate (CAS #: 52793-97-2)
    • Bornelone (CAS #: 2226-11-1)
  • Cinnamates
    • Ethyl Cinnamate (CAS #: 103-36-6)
    • 2-Ethoxyethyl-p-methoxycinnamate (Cinoxate, CAS #: 104-28-9)
    • Isoamyl P-methoxycinnamate (CAS #: 71617-10-2)
    • Diisopropyl Methyl Cinnamate (CAS #: 32580-71-5)
    • 2-Ethylhexyl Alpha-cyano-beta-phenylcinnamate (Octocrylene, CAS #: 6197-30-4)
    • Diethanolamine Methoxycinnamate (CAS #: 56265-46-4)
    • Isopropyl Methoxycinnamate (CAS #: 5466-76-2)
    • Isoamyl P-methoxycinnamate (CAS #: 71617-10-2)
    • Glyceryl Octanoate Dimethoxycinnamate
    • Ethyl Diisopropylcinnamate (CAS #: 32580-72-6)
    • Ethyl Methoxycinnamate  (CAS #: 99880-64-5)
    • Octyl Methoxycinnamate (CAS #: 5466-77-3)
  • Dibenzoylmethanes
    • Dibenzoylmethane (CAS #: 120-46-7)
    • Isopropyl Dibenzoylmethane (Eusolex, CAS #: 63250-25-9)
    • 4-tert-Butyl-4'-methoxy-dibenzoylmethane (Avobenzone, CAS #: 70356-09-1)
  • Salicylates
    • 3,3,5-Trimethylcyclohexyl Salicylate (Homosalate, CAS #: 118-56-9)
    • Benzyl Salicylate (CAS #: 118-58-1)
    • Octyl Salicylate (CAS #: 118-60-5)
    • 2-Hydroxyethyl Salicylate (CAS #: 87-28-5)
    • Menthyl Salicylate (CAS #: 89-46-3)
    • Isopropylbenzyl Salicylate  (CAS #: 94134-93-7)
  • Imidazoles
    • Phenylbenzimidazole
    • Phenylbenzimidazol-5-sulfonic Acid (CAS #: 27503-81-7)
    • Phenylbenzimidazole Tea Sulfonate  (CAS #: 73705-00-7)
    • Urocanic Acid [4-imidazoleacrylic Acid, CAS #: 104-98-3]
    • Ethyl Urocanate (CAS #: 27538-35-8)
    • Bisymidazylate (CAS #: 180898-37-7)
    • Sodium Phenylbenzimidazole Sulfonate (CAS #: 5997-53-5)
  • Others
    • Petrolatum Jelly (CAS #: 8009-03-8)
    • Ethyl 2-cyano-3,3-diphenylacrylate (Etocrilene, CAS #: 5232-99-5)
    • Diurethane Dimethacrylate (CAS #: 103597-45-1)
    • Drometrizole Trisiloxane (CAS #: 155633-54-8)
    • Bis(Ethylhexyloxyphenol Methoxyphenol) Triazine (CAS #: 187393-00-6
    • 2-(2-Hydroxy-5-methyl-phenyl)Benzotriazole  (Drometrizole, CAS #: 2440-22-4)
    • Dioctyl Butamido Triazone (CAS #: 154702-15-5)
  • Inorganic compounds (physical sunscreens)
    • Titanium dioxide
    • Zinc oxide
SALES SPECIFICATION

APPEARANCE

White to off-white crystalline powder

ASSAY

99.0% min

ACIDITY

1.0 max (mg KOH/g)

TRANSPORTATION
PACKING 25kgs in drum
HAZARD CLASS not regulated
UN NO.  
OTHER INFORMATION
Hazard Symbols: n/a, Risk Phrases: n/a, Safety Phrases: 24/25