METHYLENE BLUE

PRODUCT IDENTIFICATION

CAS NO. 61-73-4 (Anhydrous)
7220-79-3 (Trihydrate)

METHYLENE BLUE 

EINECS NO. 200-515-2
FORMULA C16H18ClN3S
MOL WT. 319.85
H.S. CODE  
TOXICITY Oral rat LD50: 1180 mg/kg
SYNONYMS Basic blue 9; Methylthioninium chloride; Swiss blue;
3,7-Bis(dimethylamino)-phenothiazin-5-ium chloride; p-Bis(dimethylamino)-phenothiazin- 5-ium chloride; C.I. 52015;
DERIVATION

 

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE dark green crystalline powder
MELTING POINT 190 C (Decomposes)
BOILING POINT  
SPECIFIC GRAVITY  
SOLUBILITY IN WATER  
AUTOIGNITION  
pH  
VAPOR DENSITY  
NFPA RATINGS  
FLASH POINT

 

STABILITY Stable under ordinary conditions. Hygroscopic

APPLICATIONS

Methylene blue, a methylated homologue of basic dye, is a cationic thiazine dye showing deep blue color in the oxidized state. It is a highly hygroscopic dark green crystalline powder having a bronze-like luster. It forms a reversible redox system with colorless leukomethylene blue (the reduced state of methylene blue). They exist in equilibrium. Methylene blue reduces the heme from methemoglobin to hemoglobin, but methemoglobin is produced when equilibrium is destroyed at high level of methylene blue. It is an electron donor or acceptor and free radical scavenger. It is clinically used to identify anatomic and pathologic structures to treat methemoglobinemia. It is used as a bacteriological in fresh frozen plasma. It is used to treat ich. It is used as a pathological stain and as a diagnostic aid in the detection of the premature rupture of fetal membranes and to identify separate amniotic sacs in multiple pregnancies. It is used as a biological and bacteriological stain, oxidation-reduction indicator as well.
SALES SPECIFICATION

APPEARANCE

dark green crystalline powder

DYE CONTENT

82.0% min

WATER

8 - 18.0%

SULFATED ASH

0.3% max

SOLUBILITY

430 (g/l in methanol)

HEAVY METALS

5ppm max

TRANSPORTATION
PACKING  
HAZARD CLASS Not regulated
UN NO.  
OTHER INFORMATION
Hazard Symbols: XN, Risk Phrases: 40, Safety Phrases: 24/25/36/37/45
BIOLOGICAL STAINS, INDICATORS

PRICE INFORMATION

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