| METHYLENE BLUE | ||
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PRODUCT IDENTIFICATION |
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| CAS NO. |
61-73-4 (Anhydrous) 7220-79-3 (Trihydrate) |
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| EINECS NO. | 200-515-2 | |
| FORMULA | C16H18ClN3S | |
| MOL WT. | 319.85 | |
| H.S. CODE | ||
| TOXICITY | Oral rat LD50: 1180 mg/kg | |
| SYNONYMS | Basic blue 9; Methylthioninium chloride; Swiss blue; | |
| 3,7-Bis(dimethylamino)-phenothiazin-5-ium chloride; p-Bis(dimethylamino)-phenothiazin- 5-ium chloride; C.I. 52015; | ||
| DERIVATION |
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CLASSIFICATION |
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PHYSICAL AND CHEMICAL PROPERTIES |
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| PHYSICAL STATE | dark green crystalline powder | |
| MELTING POINT | 190 C (Decomposes) | |
| BOILING POINT | ||
| SPECIFIC GRAVITY | ||
| SOLUBILITY IN WATER | ||
| AUTOIGNITION | ||
| pH | ||
| VAPOR DENSITY | ||
| NFPA RATINGS | ||
| FLASH POINT |
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| STABILITY | Stable under ordinary conditions. Hygroscopic | |
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APPLICATIONS |
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| Methylene blue, a methylated homologue of basic dye, is a cationic thiazine dye showing deep blue color in the oxidized state. It is a highly hygroscopic dark green crystalline powder having a bronze-like luster. It forms a reversible redox system with colorless leukomethylene blue (the reduced state of methylene blue). They exist in equilibrium. Methylene blue reduces the heme from methemoglobin to hemoglobin, but methemoglobin is produced when equilibrium is destroyed at high level of methylene blue. It is an electron donor or acceptor and free radical scavenger. It is clinically used to identify anatomic and pathologic structures to treat methemoglobinemia. It is used as a bacteriological in fresh frozen plasma. It is used to treat ich. It is used as a pathological stain and as a diagnostic aid in the detection of the premature rupture of fetal membranes and to identify separate amniotic sacs in multiple pregnancies. It is used as a biological and bacteriological stain, oxidation-reduction indicator as well. | ||
| SALES SPECIFICATION | ||
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APPEARANCE |
dark green crystalline powder | |
|
DYE CONTENT |
82.0% min | |
|
WATER |
8 - 18.0% | |
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SULFATED ASH |
0.3% max | |
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SOLUBILITY |
430 (g/l in methanol) | |
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HEAVY METALS |
5ppm max | |
| TRANSPORTATION | ||
| PACKING | ||
| HAZARD CLASS | Not regulated | |
| UN NO. | ||
| OTHER INFORMATION | ||
| Hazard Symbols: XN, Risk Phrases: 40, Safety Phrases: 24/25/36/37/45 | ||
| BIOLOGICAL STAINS, INDICATORS | ||
| PRICE INFORMATION | ||